Sir John Vane's papers were donated to the Royal Society by his widow, Lady Daphne Vane, in December 2007 and transferred to our archives through the courtesy of Roderick Flower FRS of the William Harvey Research Institute (WHRI). Vane (figure 1) founded the Research Institute, and the collection of his papers in part documents his work there. The archive is also significant in institutional terms because it was later complemented by the acquisition of papers of Professor Gustav Born FRS, a research professor at the WHRI. Professor Born is currently sorting his own papers in situ, ready for cataloguing by the archivists. However, organizational matters at the WHRI are not the only interest within the Vane papers, and a recently completed catalogue of them is now available to researchers via the Royal Society's website. This report will offer a brief overview of the life and work of Sir John Vane, as well as providing readers with a description of the contents of the collection.