Mathematics plus Cancer: An Undergraduate "Bridge" Course in Applied Mathematics

被引:0
|
作者
Stepien, Tracy L. [1 ]
Kostelich, Eric J. [2 ]
Kuang, Yang [1 ]
机构
[1] Arizona State Univ, Sch Math & Stat Sci, Tempe, AZ 85287 USA
[2] Univ Florida, Dept Math, Gainesville, FL 32611 USA
基金
美国国家科学基金会;
关键词
mathematical modeling; cancer; differential equations; undergraduate education; RESISTANT PROSTATE-CANCER; TUMOR-GROWTH; IMMUNE-SYSTEM; ANDROGEN-DEPRIVATION; CELL; MODEL; DYNAMICS; THERAPY; INTERMITTENT; LEUKEMIA;
D O I
10.1137/18M1191865
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
Mast undergraduates have limited experience with mathematical modeling. In an effort to respond to various initiatives, such as the recommendations outlined in IS. Garfunkel and M. Montgomery, eds., GAIMME: Guidelines for Assessment & Instruction in Mathematical Modeling Education, SIAM, 2016], this paper describes a course on the mathematical models of cancer growth and treatment. Among its aims is to provide a template for a "bridge" course between the traditional calculus and differential equations sequence and more advanced courses in mathematics and statistics. Prerequisites include a course in ordinary differential equations. Linear algebra is a useful corequisite but no previous programming experience is required. The content includes classical models of tumor growth as well as models for the growth of specific cancer types. Relevant research articles are provided for further study. Material for student projects and effective communication is supplied, as well as suggestions for homework assignments and computer labs. This paper aims to assist instructors in developing their own "Mathematics + Cancer" course.
引用
收藏
页码:244 / 263
页数:20
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