CYTOGENETIC BIOMONITORING IN A SERBIAN POPULATION OCCUPATIONALLY EXPOSED TO A COMPLEX MIXTURE OF PESTICIDES

被引：0
|
作者：
Jovicic, Dubravka [1 ]
Pajic, Jelena [2 ]
Rakic, Boban [2 ]
Radivojevic, Ljiljana [3 ]
Pajic, Milos [4 ]
Janjic, Vaskrsije [3 ]
Milovanovic, Aleksandar [2 ]
机构：
[1] Singidunum Univ, Fac Appl Ecol FUTURA, Belgrade, Serbia
[2] Serbian Inst Occupat Hlth Dr Dragomir Karajovic, Belgrade, Serbia
[3] Inst Pesticides & Environm Protect, Belgrade, Serbia
[4] Univ Belgrade, Fac Agr, Belgrade 11001, Serbia
来源：
GENETIKA-BELGRADE | 2013年 / 45卷 / 01期
关键词：
Occupational exposure; Human lymphocytes; chromosomal aberrations; pesticides; SISTER-CHROMATID EXCHANGE; PERIPHERAL-BLOOD LYMPHOCYTES; CHROMOSOMAL-ABERRATIONS; AGRICULTURAL-WORKERS; GENETIC-DAMAGE; RISK; GENOTOXICITY; INDIVIDUALS; MICRONUCLEI; FREQUENCY;
D O I：
10.2298/GENSR1301121J
中图分类号：
S3 [农学（农艺学）];
学科分类号：
0901 ;
摘要：
The aim of this study was the analysis of chromosomal aberrations (CA) and premature centromeric division (PCD) in people exposed to pesticides at work. The research included 26 subjects occupationally exposed to pesticides, of average age 39.89 +/- 8.66, and 32 control subjects of average age 40.57 +/- 6.57. Mann-Whitney U tests showed statistically significant differences between the groups for mean values of all the examined variables. In addition, Spearman's (non-parametric) correlation test detected a positive linear correlation between CA and PCD. The presence of mostly chromatid and isochromatid breaks in the examinees indicates continuous exposure to pesticides. The absence of complex chromosomal rearrangements points to adequate protection of the subjects at their work places.
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页码：121 / 133
页数：13
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