New Findings in Metal Complexes with Antiproliferative Activity Containing 1,3,5-Triaza-7-phosphaadamantane (PTA) and Derivative Ligands

被引：20
|
作者：
Scalambra, Franco [1 ]
Lorenzo-Luis, Pablo [2 ]
de los Rios, Isaac [3 ]
Romerosa, Antonio [1 ]
机构：
[1] Univ Almeria, Area Quim Inorgan, CIESOL, Carretera Sacramento S-N, Almeria, Spain
[2] Univ La Laguna, Dept Quim, Secc Quim Inorgan, C Astrofis Francisco Sanchez 2, San Cristobal la Laguna 38206, ULL, Spain
[3] Univ Cadiz, Dept Ciencia Mat & Ingn Met & Quim Inorgan, Fac Ciencias, Puerto Real 11510, Cadiz, Spain
来源：
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY | 2019年 / 11-12期
关键词：
PTA; dmoPTA; Complexes; Antiproliferative activity; Cancer; ARENE RUTHENIUM COMPLEXES; ARENE-RUTHENIUM(II) COMPLEXES; COORDINATION CHEMISTRY; PLATINUM(II) COMPLEXES; ANTICANCER ACTIVITY; IN-VITRO; DMOPTA; DRIVEN; AGENTS;
D O I：
10.1002/ejic.201801426
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
This minireview summarizes some of the most significant findings published in the last years on metal complexes containing PTA and PTA derivatives ligands such as dmoPTA, with antiproliferative activity [PTA = 1,3,5-triaza-7-phosphaadamantane; dmoPTA = 3,7-dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane (dmoPTA)]. Comments on other biological properties of the complexes are also included.
引用
收藏
页码：1529 / 1538
页数：10
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