Morphological and functional analysis of apoptotic cells by flow cytometry

被引：0

作者：

Mannucci, R ^{[1
]}

Nicoletti, I ^{[1
]}

机构：

[1] Univ Perugia, Sch Med, Dept Clin & Expt Med,Image Anal Lab, Sect Internal Med & Oncol, I-06122 Perugia, Italy

来源：

MINERVA BIOTECNOLOGICA | 1999年 / 11卷 / 02期

关键词：

apoptosis; programmed cell death; necrosis; flow cytometry; DNA; mitochondria; capsases;

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Apoptosis is a strictly regulated process for the removal of unnecessary, aged or damaged cells and an alteration in. the control of apoptotic cell death can entail cancer, autoimmune diseases, immune deficiency and degenerative disorders. This article briefly reviews the main, morphological and biochemical aspects of apoptotic cell death and describes several flow cytometry methods which ran be used to follow changes during the apoptotic cascade and to quantify the number of apoptotic cells.

引用

页码：113 / 127

页数：15

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