共 6 条
Genetic diversity of internalin genes in the ascB-dapE locus among Listeria monocytogenes lineages III and IV strains
被引:3
|作者:
Chen, Jianshun
[1
,2
]
Cheng, Changyong
[3
,4
]
Lv, Yonghui
[5
]
Fang, Weihuan
[3
,4
]
机构:
[1] Zhejiang Fisheries Tech Extens Ctr, Hangzhou, Zhejiang, Peoples R China
[2] Zhejiang Aquat Dis Prevent & Quarantine Ctr, Hangzhou, Zhejiang, Peoples R China
[3] Zhejiang Univ, Inst Prevent Vet Med, Hangzhou 310058, Zhejiang, Peoples R China
[4] Zhejiang Prov Key Lab Prevent Vet Med, Hangzhou, Zhejiang, Peoples R China
[5] Natl Fisheries Tech Extens Ctr, Beijing, Peoples R China
基金:
中国国家自然科学基金;
关键词:
L;
monocytogenes;
Lineages III and IV;
ascB-dapE locus;
Genetic diversity;
Evolution;
SEROVAR;
4A;
VIRULENCE;
EVOLUTION;
IDENTIFICATION;
SEQUENCE;
DISTINCT;
CLUSTER;
FAMILY;
D O I:
10.1002/jobm.201200137
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
Listeria monocytogenes is an important foodborne pathogen encompassing four phylogenetic lineages. Lineages III and IV are rare, but have been reported to show considerable biodiversity, providing important clues for the evolutionary history in Listeria. In this study, analysis of the ascB-dapE locus reveals genetic diversity in lineages III and IV, and is consistent with the classification of sublineages. Four of the six genetic patterns (two of sublineage IIIC and two of lineage IV) are specific to these two lineages. The ascB-dapE locus suggests a hot spot for genome diversification, and serves as an attractive molecular marker for better understanding of the biodiversity and population structure of lineages III and IV strains.
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页码:778 / 784
页数:7
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