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Cell fate determination from stem cells

被引：100
|
作者：
Wagers, AJ
Christensen, JL
Weissman, IL
机构：
[1] Stanford Univ, Dept Pathol, Sch Med, Stanford, CA 94305 USA
[2] Stanford Univ, Dept Dev Biol, Sch Med, Stanford, CA 94305 USA
来源：
GENE THERAPY | 2002年 / 9卷 / 10期
关键词：
stem cells; progenitors; hematopoiesis; self-renewal; differentiation; migration;
D O I：
10.1038/sj.gt.3301717
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In the adult, tissue-specific stem cells are thought to be responsible for the replacement of differentiated cells within continuously regenerating tissues, such as the liver, skin, and blood system. In this review, we will consider the factors that influence stem cell fate, taking as a primary example the cell fate determination of hematopoietic stem cells.
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收藏
页码：606 / 612
页数：7
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