Synthesis of Low-Cost Iron Oxide: Chitosan Nanocomposite for Antibacterial Activity

被引:28
|
作者
Kavitha, Al [1 ]
Prabu, H. Gurumallesh [1 ]
Babu, S. Ananda [1 ]
机构
[1] Alagappa Univ, Sch Chem Sci, Dept Ind Chem, Karaikkudi 630003, Tamil Nadu, India
关键词
Antibacterial; characterization; chitosan; iron oxide nanoparticles; MAGNETIC NANOPARTICLES; PARTICLES; BIOSENSOR; DEXTRAN; FE3O4;
D O I
10.1080/00914037.2012.670816
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
alpha-iron oxide nanoparticles were synthesized by the self-assembly method and characterized. The average particle size was found to be 27-30nm by XRD and AFM. The alpha-Fe2O3 nanoparticles were dispersed into the prepared chitosan (CH) solution. After the dispersion, the CH-alpha-Fe2O3 nanocomposite was subjected to characterizations such as UV-Visible, FT-IR, XRD, and SEM with EDX. The antibacterial activity was checked for the prepared CH-alpha-Fe2O3 nanocomposite by zone of inhibition method (AATCC 147). The CH-alpha-Fe2O3 nanocomposite showed improved antibacterial activity against gram-positive bacteria (Staphylococcus aureus) and gram-negative bacteria (Escherichia coli) when compared to the individual CH and alpha-Fe2O3 nanoparticles.
引用
收藏
页码:45 / 49
页数:5
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