The Cognitive Impairment in Patients with Chronic Obstructive Pulmonary Disease

Background: Actuality: the cognitive impairment have important role among extrapulmonary manifestations in chronic obstructive pulmonary disease (COPD). At the moment there is no clear understanding of the role of chronic obstructive pulmonary disease in their formation. Aim: To study the role of chronic obstructive pulmonary disease in cognitive impairment formation and their features at various stages of COPD. Methods: Study included 55 men divided into two groups: 28 patients with chronic obstructive pulmonary disease and 27 healthy volunteers in the control group. Were performed general clinical examination, spirometry, pulse oximetry, a CAT assessment and cognitive assessment using the MoCA test. Results: In patients with COPD, the cognitive function decreased according to the MoCA test (24 points against 27 points in the control group, p=0.003). The greatest contribution to the cognitive functions reduction in patients with COPD has motor disorders (p = 0.032), memory changes (p = 0.016), coordination disorders (p = 0.010), and sleep disturbances (p <0.001). It was found that in COPD patients the total score of the MoCA test correlated with the scores of the CAT test score (r =-0.580, p = 0.001) and saturation (r = 0.420, p = 0.026). Conclusion: In patients with COPD, there is cognitive function decreasing. An increase in bronchial obstruction severity and amount of symptoms combines with progressive decrease in cognitive functions. In patients with chronic obstructive pulmonary disease, sleep and memory disorders are more frequent, speech and the ability to abstract, and visuospatial and executive skills suffer.