Chitotriosidase as a marker of disease activity in sarcoidosis

被引：14
|
作者：
Brunner, Juergen
Scholl-Buergi, Sabine
Prelog, Martina
Zimmerhackl, Lothar-Bernd
机构：
[1] Innsbruck Med Sch, Dept Pediat, Div Rheumatol Nephrol Infectiol & Endocrinol, A-6020 Innsbruck, Austria
[2] Innsbruck Med Sch, Dept Pediat, Div Neonatol & Neuropediat, A-6020 Innsbruck, Austria
来源：
RHEUMATOLOGY INTERNATIONAL | 2007年 / 27卷 / 12期
关键词：
juvenile sarcoidosis; chitotriosidase;
D O I：
10.1007/s00296-007-0318-5
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Sarcoidosis is a chronic granulomatous inflammation. The clinical spectrum in childhood is heterogeneous. Angiotensin converting enzyme activity is used as a marker for disease activity. Human chitotriosidase is produced in macrophages. In this study, serum chitotriosidase levels were significantly higher in active sarcoidosis than in inactive disease or healthy controls. Serum chitotriosidase concentrations may be a useful marker for monitoring disease activity in sarcoidosis.
引用
收藏
页码：1185 / 1186
页数：2
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