Adoptive Transfer of Gene-Modified T-Cells Engineered to Express High-Affinity TCRs for Cancer-Testis Antigens (CTAs) NY-ESO-1 or Lage-1, in MM Patients Post Auto-SCT

被引：0

作者：

Rapoport, Aaron P. ^{[1
]}

Stadtmauer, Edward A.

Vogl, Dan T. ^{[2
]}

Weiss, Brendan M. ^{[2
]}

Binder-Scholl, Gwendolyn K. ^{[3
]}

Brewer, Joanna E. ^{[4
]}

Bennett, Alan D. ^{[4
]}

Gerry, Andrew B. ^{[4
]}

Pumphrey, Nick J. ^{[4
]}

Smethurst, Dominic P. ^{[4
]}

Tayton-Martin, Helen K. ^{[4
]}

Lilliam, Ribeiro C. ^{[3
]}

Veloso, Elizabeth ^{[2
]}

Zheng, Zhaohui ^{[5
]}

Badros, Ashraf Z. ^{[1
]}

Yanovich, Saul ^{[1
]}

Akpek, Gorgun ^{[1
]}

McConville, Holly ^{[2
]}

Kerr, Naseem ^{[2
]}

Philip, Sunita ^{[1
]}

Betts, Kelly-Marie ^{[1
]}

Westphal, Sandra ^{[1
]}

Kalos, Michael ^{[2
]}

Levine, Bruce L. ^{[5
]}

Jakobsen, Bent K. ^{[4
]}

June, Carl H. ^{[5
]}

机构：

[1] Univ Maryland, Greenebaum Canc Ctr, Baltimore, MD 21201 USA

[2] Univ Penn, Abramson Canc Ctr, Perelman Sch Med, Philadelphia, PA 19104 USA

[3] Adaptimmune LLC, Philadelphia, PA USA

[4] Adaptimmune Ltd, Abingdon, Oxon, England

[5] Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA

来源：

BLOOD | 2012年 / 120卷 / 21期

关键词：

D O I：

10.1182/blood.V120.21.472.472

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

472

引用

下载

页数：2

共 4 条

[1] ADOPTIVE TRANSFER OF GENE-MODIFIED T-CELLS ENGINEERED TO EXPRESS HIGH-AFFINITY TCR'S FOR CANCER-TESTIS ANTIGENS NY-ESO-1 OR LAGE-1, IN MULTIPLE MYELOMA (MM) PATIENTS POST AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANT (ASCT)
Levine, B. L.
Rapoport, A. P.
Stadtmauer, E. A.
Vogl, D. T.
Weiss, B.
Binder-Scholl, G. K.
Smethurst, D. P.
Brewer, J. E.
Bennett, A. D.
Gerry, A. B.
Pumphrey, N. J.
Tayton-Martin, H. K.
Ribiero, L.
Veloso, E. A.
Finklestein, J.
Kulikovskaya, I.
Gupta, M.
Suppa, E.
Mikheeva, T.
Zheng, Z.
Brennan, A. L.
Bersenev, A.
Tripic, T.
Cribioli, E.
Cotte, J.
Badros, A. Z.
Yanovich, S.
Akpek, G.
McConville, H.
Kerr, N.
Philip, S.
Betts, K.
Westphal, S.
Kalos, M.
Jacobsen, B. K.
June, C. H.
CYTOTHERAPY, 2013, 15 (04) : S13 - S13
[2] Safety and Correlates of Clinical Response in an Early Phase Clinical Trial in Multiple Myeloma Patients Post Auto-SCT and Adoptive Immunotherapy with Engineered T Cells Expressing an HLA-A2 Restricted Affinity-Enhanced TCR for LAGE-1 and NY-ESO-1
Levine, Bruce L.
Rapoport, Aaron P.
Stadtmauer, Edward A.
Vogl, Dan T.
Weiss, Brendan
Binder-Scholl, Gwendolyn K.
Smethurst, Dominic P.
Finkelstein, Jeffrey
Kulikovskaya, Irina
Gupta, Minnal
Suppa, Erica
Brewer, Joanna E.
Bennett, Alan D.
Gerry, Andrew B.
Pumphrey, Nick J.
Tayton-Martin, Helen K.
Williams, Daniel
Zheng, Zhaohui
Badros, Ashraf Z.
Yanovich, Saul
Akpek, Gorgon
Kalos, Michael
Jakobsen, Bent K.
June, Carl H.
MOLECULAR THERAPY, 2013, 21 : S114 - S114
[3] Prolonged T Cell Persistence, Homing to Marrow and Selective Targeting of Antigen Positive Tumor in Multiple Myeloma Patients Following Adoptive Transfer of T Cells Genetically Engineered to Express an Affinity-Enhanced T Cell Receptor Against the Cancer Testis Antigens NY-ESO-1 and Lage-1
Kalos, Michael
Rapoport, Aaron P.
Stadtmauer, Edward A.
Vogl, Dan T.
Weiss, Brendan M.
Binder-Scholl, Gwendolyn K.
Smethurst, Dominic P.
Kulikovskaya, Irina
Gupta, Minnal
Macatee, Timothy L.
Finklestein, Jeffrey M.
Brewer, Joanna E.
Bennett, Alan D.
Gerry, Andrew B.
Pumphrey, Nick J.
Tayton-Martin, Helen K.
Veloso, Elizabeth
Meng, Zhaohui
Badros, Ashraf Z.
Yanovich, Saul
Akpek, Gorgun
McConville, Holly
Philip, Sunita
Levine, Bruce L.
Jakobsen, Bent K.
June, Carl H.
BLOOD, 2012, 120 (21)
[4] Autologous aGVHD Associated with Infusion of T-Cells with Engineered Specificity for NY-ESO-1 and LAGE-1 Following High-Dose Melphalan and ASCT in Patients with Multiple Myeloma
Garfall, Alfred L.
Kalos, Michael
Furth, Emma E.
Vogl, Dan
Weiss, Brendan
Cantor, Joshua
Gupta, Minnal
Levine, Bruce
Rapoport, Aaron
Ribeiro, Lilliam
Jakobsen, Bent
Smethurst, Dominic
Binder-Scholl, Gwendolyn
June, Carl H.
Stadtmauer, Edward A.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2013, 19 (02) : S134 - S134

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