Seeking therapeutic synergy in BRAF mutant colorectal cancer

被引：6
|
作者：
Elez, Elena [1 ]
Ros, Javier [1 ]
Tabernero, Josep [1 ]
机构：
[1] Vall dHebron Hosp Campus, Inst Oncol VHIO, Med Oncol Dept, Barcelona, Spain
来源：
NATURE MEDICINE | 2023年 / 29卷 / 02期
关键词：
D O I：
10.1038/s41591-022-02192-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In a phase I trial, the combination of dabrafenib, trametinib and spartalizumab uncovers the crosstalk between the MAPK pathway and the immune system, which offers a promising new strategy to improve clinical outcomes.
引用
收藏
页码：307 / 308
页数：2
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