Current concepts and advances in dermatomyositis: a dermatological perspective

被引:2
|
作者
Lim, D. [1 ,2 ]
Fiorentino, D. [3 ]
Werth, V. [1 ,2 ,4 ]
机构
[1] Corporal Michael J Crescenz Dept Vet Affairs Med C, Dermatol, Philadelphia, PA USA
[2] Univ Penn, Perelman Sch Med, Philadelphia, PA USA
[3] Stanford Univ, Sch Med, Dept Dermatol, Redwood City, CA USA
[4] Perelman Ctr Adv Med, Dept Dermatol, Suite 1-330A,3400 Civ Ctr Blvd, Philadelphia, PA 19104 USA
关键词
clinically amyopathic dermatomyositis; skin-predominant dermatomyositis; dermatomyositis; INTERSTITIAL LUNG-DISEASE; SEVERITY INDEX CDASI; REFRACTORY CUTANEOUS DERMATOMYOSITIS; IDIOPATHIC INFLAMMATORY MYOPATHIES; CANCER-ASSOCIATED DERMATOMYOSITIS; INTRAVENOUS IMMUNE GLOBULIN; JUVENILE DERMATOMYOSITIS; JAPANESE PATIENTS; CLINICAL-MANIFESTATIONS; ADULT DERMATOMYOSITIS;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Dermatomyositis (DM) is an auto - immune disorder in which clinically amyopathic DM, characterised by hall- mark cutaneous findings in the absence of clinical weakness, represents 20% of patients. This review will highlight current concepts and recent advances made in DM from a dermatological perspective, with a discussion of skin - predominant DM and its distinct chal- lenges regarding diagnosis and man- agement as well as their implications in clinical trials. An update will be pre- sented with respect to classification cri- teria, pathogenesis in cutaneous DM, myositis-specific autoantibodies and their associations with cutaneous find- ings, skin-specific outcome measures and new therapeutics with their efficacy in skin disease.
引用
收藏
页码:359 / 369
页数:11
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