Maternal hepatic immunology during pregnancy

被引:1
|
作者
Yang, Ling [1 ]
Meng, Yao [1 ]
Shi, Yuxiang [1 ]
Fang, Hongxu [1 ]
Zhang, Leying [1 ]
机构
[1] Hebei Univ Engn, Sch Life Sci & Food Engn, Handan, Peoples R China
来源
FRONTIERS IN IMMUNOLOGY | 2023年 / 14卷
关键词
hormone; immunology; liver; pregnancy; growth factor; BINDING PROTEIN EXPRESSION; T-CELL TOLERANCE; DENDRITIC CELLS; MELATONIN RECEPTORS; ENDOTHELIAL-CELLS; GENE-EXPRESSION; MAMMARY-GLAND; LIVER GROWTH; GH RECEPTOR; ACTIVATION;
D O I
10.3389/fimmu.2023.1220323
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The liver plays pivotal roles in immunologic responses, and correct hepatic adaptations in maternal immunology are required during pregnancy. In this review, we focus on anatomical and immunological maternal hepatic adaptations during pregnancy, including our recent reports in this area. Moreover, we summarize maternal pregnancy-associated liver diseases, including hyperemesis gravidarum; intrahepatic cholestasis of pregnancy; preeclampsia, specifically hemolysis, elevated liver enzymes, and low platelet count syndrome; and acute fatty liver of pregnancy. In addition, the latest information about the factors that regulate hepatic immunology during pregnancy are reviewed for the first time, including human chorionic gonadotropin, estrogen, progesterone, growth hormone, insulin like growth factor 1, oxytocin, adrenocorticotropic hormone, adrenal hormone, prolactin, melatonin and prostaglandins. In summary, the latest progress on maternal hepatic anatomy and immunological adaptations, maternal pregnancy-associated diseases and the factors that regulate hepatic immunology during pregnancy are discussed, which may be used to prevent embryo loss and abortion, as well as pregnancy-associated liver diseases.
引用
收藏
页数:13
相关论文
共 50 条
  • [1] Immunology of hepatic diseases during pregnancy
    Lars Bremer
    Christoph Schramm
    Gisa Tiegs
    [J]. Seminars in Immunopathology, 2016, 38 : 669 - 685
  • [2] Immunology of hepatic diseases during pregnancy
    Bremer, Lars
    Schramm, Christoph
    Tiegs, Gisa
    [J]. SEMINARS IN IMMUNOPATHOLOGY, 2016, 38 (06) : 669 - 685
  • [3] Maternal obesity during pregnancy: Are there implications for maternal hepatic mitochondrial activity?
    Diniz, M.
    Grilo, L. F.
    Martins, J. D.
    Ford, S.
    Nathanielsz, P. W.
    Oliveira, P. J.
    Pereira, S. P.
    [J]. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2020, 50 : 32 - 32
  • [4] PREGNANCY IMMUNOLOGY AND MATERNAL ALLOIMMUNE RESPONSES
    Kumpel, B. M.
    [J]. VOX SANGUINIS, 2012, 103 : 7 - 7
  • [5] IMMUNOLOGY OF PREGNANCY - FOETO-MATERNAL BARRIER
    CURRIE, GA
    [J]. PROCEEDINGS OF THE ROYAL SOCIETY OF MEDICINE-LONDON, 1968, 61 (11P2): : 1206 - &
  • [6] Maternal and foetal outcomes, biochemistry and immunology changes during pregnancy in patients with autoimmune hepatitis
    Olsen, Kathryn
    Hodson, James
    Ronca, Vincenzo
    Hayden, Jennifer
    Wootton, Grace
    Knox, Ellen
    El-Sherif, Omar
    Armstrong, Matthew
    Johnston, Tracey
    Ferguson, James
    Thompson, Fiona
    Adams, David
    Oo, Ye
    [J]. JOURNAL OF HEPATOLOGY, 2020, 73 : S477 - S478
  • [7] Hepatic oxidative response to maternal obesity during pregnancy in an ewe model
    Grilo, Luis
    Pereira, Susana P.
    Martins, Joao D.
    Cavallaro, Chiara H.
    Cardoso, Ines
    Baldeiras, Ines
    Cunha-Oliveira, Teresa
    Ford, Stephen
    Nathanielsz, Peter W.
    Oliveira, Paulo J.
    [J]. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2019, 49 : 107 - 108
  • [8] PHAGOCYTOSIS OF MATERNAL LYMPHOCYTES BY THE FETAL TROPHOBLAST AND THE IMMUNOLOGY OF PREGNANCY
    MARKOVIC, B
    GRIZIOTIS, G
    NICHOLLS, EM
    [J]. MEDICAL HYPOTHESES, 1983, 10 (03) : 337 - 345
  • [9] DISCUSSION OF IMMUNOLOGY OF PREGNANCY - FOETO-MATERNAL BARRIER
    CURZEN, P
    CURRIE, GA
    DESA, DJ
    ADINOLFI, M
    [J]. PROCEEDINGS OF THE ROYAL SOCIETY OF MEDICINE-LONDON, 1968, 61 (11P2): : 1211 - +
  • [10] Immunology of neuromyelitis optica during pregnancy
    Davoudi, Vahid
    Keyhanian, Kiandokht
    Bove, Riley M.
    Chitnis, Tanuja
    [J]. NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION, 2016, 3 (06):