Phenothiazine derivatives of 1,8-naphthalic anhydride: Synthesis, characterization and antimicrobial studies

被引:3
|
作者
Marinov, Marin [1 ]
Nikolova, Liana [2 ]
Kostova, Liana [2 ]
Stoyanov, Neyko [2 ]
机构
[1] Agr Univ, Fac Plant Protect & Agroecol, Dept Chem & Phytopharm, Plovdiv, Bulgaria
[2] Angel Kanchev Univ Ruse, Dept Chem Food & Biotechnol, Razgrad Branch, Ruse, Bulgaria
关键词
Phenothiazine; 1; 8-naphthalic anhydride; antimicrobial activity; DNA; RECOGNITION;
D O I
10.1080/10426507.2022.2116707
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The following article describes the synthesis of phenothiazine derivatives of 1,8-naphthalic anhydride. The target compounds were prepared by an interaction of 6-(10H-phenothiazin-10-yl)-1H,3H-naphtho[1,8-cd]pyran-1,3-dione and its derivatives with H2O2, H2NNH2, HNO3/CH3COOH and HCl, respectively. The compounds obtained were spectroscopically characterized by IR, H-1 NMR and C-13 NMR including C-13 DEPT 135. Their antimicrobial activity against Gram-positive and Gram-negative bacteria, yeasts and molds have also been studied.
引用
收藏
页码:128 / 136
页数:9
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