Regioselective Synthesis of Quercetin and Myricetin Derivatives

被引：2
|
作者：
Pechinskii, S. V. [1 ]
Kuregyan, A. G. [1 ]
Oganesyan, E. T. [1 ]
机构：
[1] Volgograd Med State Univ, Med Pharmaceut Inst, Pyatigorsk Branch, Pyatigorsk 357532, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2023年 / 93卷 / 02期
关键词：
quercetin; myricetin; esterification; Novozyme; 435; PASS; PHARMACOKINETIC PROPERTIES; STABILITY; CANCER; EPIGALLOCATECHIN-3-GALLATE; ESTERS;
D O I：
10.1134/S1070363223020032
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A regioselective method for the synthesis of esters of quercetin and myricetin at the hydroxy group in the position 3 was developed. As acids participating in the esterification reaction, 2-hydroxybenzoic (salicylic), 4-hydroxybenzoic, 2,6-dihydroxybenzoic, 3,4-dihydroxybenzoic (procatechuic), 3,4,5-trihydroxybenzoic (gallic) acids were used. A new series of quercetin and myricetin esters were obtained.
引用
收藏
页码：245 / 252
页数：8
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