Nanoparticles as carriers of photosensitizers to improve photodynamic therapy in cancer

被引:2
|
作者
Truong, Duy Hieu [1 ]
Tran, Phuong Thi Thu [2 ]
Tran, Tuan Hiep [1 ]
机构
[1] Phenikaa Univ, Fac Pharm, Hanoi, Vietnam
[2] Univ Sci & Technol Hanoi, Vietnam Acad Sci & Technol, Dept Life Sci, Hanoi, Vietnam
关键词
Photodynamic therapy; photosensitizers; cancer; nanoparticles; nanomedicine; nanotechnology; PHOTOTHERMAL CONVERSION EFFICIENCY; SOLID TUMOR MICROENVIRONMENT; GROWTH-FACTOR; ALBUMIN-MNO2; NANOPARTICLES; POLYPYRROLE NANOPARTICLES; LOCALIZED DELIVERY; MNO2; CARBON DOTS; HYPOXIA; DRUG;
D O I
10.1080/10837450.2024.2322570
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Photodynamic therapy (PDT) has emerged as a promising non invasive therapeutic approach for cancer treatment, offering unique advantages over conventional treatments. The combination of light activation and photosensitizing agents allows for targeted and localized destruction of cancer cells, reducing damage to surrounding healthy tissues. In recent years, the integration of nanoparticles with PDT has garnered significant attention due to their potential to enhance therapeutic outcomes. This review article aims to provide a comprehensive overview of the current state-of-the-art in utilizing nanoparticles for photodynamic therapy in cancer treatment. We summarized various nanoparticle-based approaches, their properties, and their implications in optimizing PDT efficacy, and discussed challenges and prospects in the field.
引用
收藏
页码:221 / 235
页数:15
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