Perovskite Nanoparticles and Their Use in Efficient Electro-Catalytic Oxidation of Tadalafil

PrCrO3 perovskite-type nanoparticles were prepared by the co-precipitation method. In the hexagonal phase, highly crystalline particles with an average particle size of 80-90 nm were observed from the x-ray diffraction pattern. Transmission electron microscopic images showed irregularly shaped, smooth surfaces, with narrow-size-distributed nanocrystals. Phase purity, thermal stability, and optical activity were monitored by Fourier transform infrared spectroscopy, thermogravimetric analysis, and UV/visible absorption spectroscopy. The electro-catalytic properties of the fabricated PrCrO3/glassy carbon electrode (GCE) were investigated by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). CV and EIS profiles were useful for monitoring catalytic activity over a wide tadalafil concentration range from 7.85 & mu;M to 1000 & mu;M. The fabricated electrochemical sensor exhibited a linear detection range, a detection limit of 7.85 & mu;M, excellent electro-catalytic activity, time response, real sample analysis, and sustainability over 11 consecutive cycles, and stability was observed under potentials of 5 eV, 10 eV, 20-100 eV, and 150 eV. CV results showed excellent electro-catalytic behavior because its oxygen-deficient crystal lattice produces oxygen vacancies, which assist in electron communication over the electrode surface. The electrochemical results of the perovskite/GCE suggest their future use in a comprehensive range including electrochemical biosensors, electro-catalysts, solid fuel cells, solar cells, supercapacitors, and corrosion protection layers.