Biotite: new tools for a versatile Python']Python bioinformatics library

被引:4
|
作者
Kunzmann, Patrick [1 ]
Mueller, Tom David [2 ]
Greil, Maximilian
Krumbach, Jan Hendrik [1 ]
Anter, Jacob Marcel [1 ]
Bauer, Daniel [1 ]
Islam, Faisal [1 ]
Hamacher, Kay [1 ]
机构
[1] Tech Univ Darmstadt, Computat Biol & Simulat, Schnittspahnstr 2, D-64287 Darmstadt, Germany
[2] Eberhard Karls Univ Tubingen, Dept Comp Sci, Sand 14, D-72076 Tubingen, Germany
关键词
Open source; !text type='Python']Python[!/text; Structural bioinformatics; Sequence analysis; MULTIPLE SEQUENCE ALIGNMENT; RNA STRUCTURES; DYNAMICS; SEARCH; CLASSIFICATION; IDENTIFICATION; DICTIONARY; SIMILARITY; ALGORITHM; ACCURACY;
D O I
10.1186/s12859-023-05345-6
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
BackgroundBiotite is a program library for sequence and structural bioinformatics written for the Python programming language. It implements widely used computational methods into a consistent and accessible package. This allows for easy combination of various data analysis, modeling and simulation methods.ResultsThis article presents major functionalities introduced into Biotite since its original publication. The fields of application are shown using concrete examples. We show that the computational performance of Biotite for bioinformatics tasks is comparable to individual, special purpose software systems specifically developed for the respective single task.ConclusionsThe results show that Biotite can be used as program library to either answer specific bioinformatics questions and simultaneously allow the user to write entire, self-contained software applications with sufficient performance for general application.
引用
收藏
页数:19
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