Statistical evaluation of cluster formation of relapse in neuromyelitis optica spectrum disorder

被引：0
|
作者：
Akaishi, Tetsuya [1 ]
Nakashima, Ichiro [2 ]
机构：
[1] Tohoku Univ, Dept Neurol, Sendai, Japan
[2] Tohoku Med & Pharmaceut Univ, Dept Neurol, Sendai, Japan
来源：
NEURAL REGENERATION RESEARCH | 2024年 / 19卷 / 09期
关键词：
D O I：
10.4103/1673-5374.390980
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Summary: In this report, we presented statistical methods for evaluating the presence of uneven cluster formation in the clinical attacks of relapsing diseases. Both goodness-of-fit and KS tests revealed a significant difference between the observed and expected frequencies, suggesting that relapse occurrence in anti-AQP4-positive NMOSD cannot be considered a Poisson process. Further studies are warranted to determine the benefit of distinguishing the attack cluster period from other non-cluster periods to optimize strategies for relapse prevention. © 2024 Wolters Kluwer Medknow Publications. All rights reserved.
引用
收藏
页码：1888 / 1889
页数：2
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