widefield;
ultra-widefield;
imaging;
retina;
field of view;
diabetic retinopathy;
RETINOPATHY;
D O I:
10.3390/life13010202
中图分类号:
Q [生物科学];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
Diabetic retinopathy (DR) often causes a wide range of lesions in the peripheral retina, which can be undetected when using a traditional fundus camera. Widefield (WF) and Ultra-Widefield (UWF) technologies aim to significantly expand the photographable retinal field. We conducted a geometrical analysis to assess the field of view (FOV) of WF and UWF imaging, comparing it to the angular extension of the retina. For this task, we shot WF images using the Zeiss Clarus 500 fundus camera (Carl Zeiss Meditec, Jena, Germany). Approximating the ocular bulb to an ideal sphere, the angular extension of the theoretically photographable retinal surface was 242 degrees. Performing one shot, centered on the macula, it was possible to photograph a retinal surface of similar to 570 mm(2), with a FOV of 133 degrees. Performing four shots with automatic montage, we obtained a retinal surface area of similar to 1100 mm(2) and an FOV of 200 degrees. Finally, performing six shots with semi-automatic montage, we obtained a retinal surface area of similar to 1400 mm(2) and an FOV of 236.27 degrees, which is close to the entire surface of the retina. WF and UWF imaging allow the detailed visualization of the peripheral retina, with significant impact on the diagnosis and management of DR.
机构:
IRCCS Osped San Raffaele, Dept Ophthalmol, Milan, Italy
Med Univ Wien, Dept Ophthalmol, Vienna, AustriaNorthwestern Univ, Dept Ophthalmol, Feinberg Sch Med, Chicago, IL 60611 USA
Ritter, Markus
Ghossein, Cybele
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机构:
Northwestern Univ, Dept Med, Div Nephrol & Hypertens, Feinberg Sch Med, Chicago, IL 60611 USANorthwestern Univ, Dept Ophthalmol, Feinberg Sch Med, Chicago, IL 60611 USA
Ghossein, Cybele
Aschauer, Constantin
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机构:
Med Univ Wien, Div Nephrol & Dialysis, Univ Klin Innere Med 3, Vienna, AustriaNorthwestern Univ, Dept Ophthalmol, Feinberg Sch Med, Chicago, IL 60611 USA
Aschauer, Constantin
Jampol, Lee M.
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机构:
Northwestern Univ, Dept Ophthalmol, Feinberg Sch Med, Chicago, IL 60611 USANorthwestern Univ, Dept Ophthalmol, Feinberg Sch Med, Chicago, IL 60611 USA
机构:
Weill Cornell Med Coll, Dept Ophthalmol, New York, NY USAWeill Cornell Med Coll, Dept Ophthalmol, New York, NY USA
Kang, Kai B.
Wessel, Matthew M.
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机构:
Weill Cornell Med Coll, Dept Ophthalmol, New York, NY USAWeill Cornell Med Coll, Dept Ophthalmol, New York, NY USA
Wessel, Matthew M.
Tong, Jianping
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机构:
Zhejiang Univ, Coll Med, Affiliated Hosp 1, Dept Ophthalmol, Hangzhou 310003, Zhejiang, Peoples R ChinaWeill Cornell Med Coll, Dept Ophthalmol, New York, NY USA
Tong, Jianping
D'Amico, Donald J.
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机构:
Weill Cornell Med Coll, Dept Ophthalmol, New York, NY USAWeill Cornell Med Coll, Dept Ophthalmol, New York, NY USA
D'Amico, Donald J.
Chan, R. V. Paul
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机构:
Weill Cornell Med Coll, Dept Ophthalmol, New York, NY USAWeill Cornell Med Coll, Dept Ophthalmol, New York, NY USA
机构:
Med Ctr Ophthalmol Associates, Dept Ophthalmol, San Antonio, TX USAMed Ctr Ophthalmol Associates, Dept Ophthalmol, San Antonio, TX USA
Singer, Michael
Sagong, Min
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机构:
UCLA, David Geffen Sch Med, Doheny Eye Inst, Dept Ophthalmol, 1450 San Pablo St,DEI 3623, Los Angeles, CA 90033 USA
Yeungnam Univ, Coll Med, Dept Ophthalmol, Daegu, South KoreaMed Ctr Ophthalmol Associates, Dept Ophthalmol, San Antonio, TX USA
Sagong, Min
van Hemert, Jano
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机构:
Optos Plc, Dunfermline, Fife, ScotlandMed Ctr Ophthalmol Associates, Dept Ophthalmol, San Antonio, TX USA
van Hemert, Jano
Kuehlewein, Laura
论文数: 0引用数: 0
h-index: 0
机构:
UCLA, David Geffen Sch Med, Doheny Eye Inst, Dept Ophthalmol, 1450 San Pablo St,DEI 3623, Los Angeles, CA 90033 USA
Univ Tubingen, Ctr Ophthalmol, Inst Ophthalm Res, Tubingen, GermanyMed Ctr Ophthalmol Associates, Dept Ophthalmol, San Antonio, TX USA
Kuehlewein, Laura
Bell, Darren
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h-index: 0
机构:
Med Ctr Ophthalmol Associates, Dept Ophthalmol, San Antonio, TX USAMed Ctr Ophthalmol Associates, Dept Ophthalmol, San Antonio, TX USA
Bell, Darren
Sadda, SriniVas R.
论文数: 0引用数: 0
h-index: 0
机构:
UCLA, David Geffen Sch Med, Doheny Eye Inst, Dept Ophthalmol, 1450 San Pablo St,DEI 3623, Los Angeles, CA 90033 USAMed Ctr Ophthalmol Associates, Dept Ophthalmol, San Antonio, TX USA