Impact of independent early stage extracorporeal cardiopulmonary resuscitation in the emergency department following the establishment of an extracorporeal life support team
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作者:
Liu, Zhan-Xiao
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机构:
Aerosp Ctr Hosp, Dept Emergency Med, Beijing 100049, Peoples R ChinaAerosp Ctr Hosp, Dept Emergency Med, Beijing 100049, Peoples R China
Liu, Zhan-Xiao
[1
]
Yang, Ya
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Aerosp Ctr Hosp, Dept Emergency Med, Beijing 100049, Peoples R ChinaAerosp Ctr Hosp, Dept Emergency Med, Beijing 100049, Peoples R China
Yang, Ya
[1
]
Song, Huan-Huan
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Aerosp Ctr Hosp, Dept Emergency Med, Beijing 100049, Peoples R ChinaAerosp Ctr Hosp, Dept Emergency Med, Beijing 100049, Peoples R China
Song, Huan-Huan
[1
]
Liu, Wei
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Aerosp Ctr Hosp, Dept Emergency Med, Beijing 100049, Peoples R ChinaAerosp Ctr Hosp, Dept Emergency Med, Beijing 100049, Peoples R China
Liu, Wei
[1
]
Sun, Peng
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Aerosp Ctr Hosp, Dept Emergency Med, Beijing 100049, Peoples R ChinaAerosp Ctr Hosp, Dept Emergency Med, Beijing 100049, Peoples R China
Sun, Peng
[1
]
Lin, Cai-Wei
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Aerosp Ctr Hosp, Dept Emergency Med, Beijing 100049, Peoples R ChinaAerosp Ctr Hosp, Dept Emergency Med, Beijing 100049, Peoples R China
Lin, Cai-Wei
[1
]
机构:
[1] Aerosp Ctr Hosp, Dept Emergency Med, Beijing 100049, Peoples R China
Early stage;
Emergency department;
Extracorporeal cardiopulmonary resuscitation;
Independent;
Team building;
OXYGENATION;
ASSOCIATION;
D O I:
10.1016/j.heliyon.2023.e23411
中图分类号:
O [数理科学和化学];
P [天文学、地球科学];
Q [生物科学];
N [自然科学总论];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
Objective: In this paper, we present a comprehensive overview of our experience in establishing and leading distinct extracorporeal cardiopulmonary resuscitation (ECPR)-related teams to independently handle ECPR in the early stages in the emergency department.Methods: A retrospective analysis was conducted on the clinical data of 29 patients who underwent ECPR treatment in the emergency room between May 2018 and April 2022. A control group, consisting of 10 patients treated between May 2018 and September 2019 was managed using a standard rescue coordination mode. The 19 patients who received ECPR between October 2019 and April 2022 were treated by members of the department's 24-h extracorporeal life support team. We compared the implementation and operational challenges faced by the two groups, including item preparation, circuit setup, and ECPR initiation times, among other factors.Results: Gender, age, cardiac arrest risk factors, and other baseline data did not significantly differ between the two groups. Extracorporeal membrane oxygenation (ECMO) pipeline prefilling time (from 35.27 +/- 10.34 to 13.46 +/- 5.32), ECPR establishment time (from 62.35 +/- 29.61 to 30.98 +/- 13.41), and item preparation time (from 16.42 +/- 9.78 to 3.19 +/- 1.49) all considerably decreased when compared to the control group. The rate of return of spontaneous circulation recovery rose from 37.50 % to 77.78 % (P < 0.05). The consequences of gastrointestinal and pulmonary bleeding were greatly reduced while ECPR was being used, and the difference was statistically significant (P < 0.05). Significant improvements were made in the ECPR weaning rate (from 25.00 % to 38.89 %) and survival rate (from 20.0 % to 36.8 %).Conclusion: The establishment of a 24-h extracorporeal life support team significantly reduced the time needed for rescue during the early stage of independent setup of ECPR in the emergency department and serves as a guide for effective care of critically ill patients.
机构:
Univ Utah Hlth, Dept Pharm Serv, 50 North Med Dr A-050, Salt Lake City, UT 84132 USAUniv Utah Hlth, Dept Pharm Serv, 50 North Med Dr A-050, Salt Lake City, UT 84132 USA
Terry, Kimberly
Lonardo, Nick
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机构:
Univ Utah Hlth, Dept Pharm Serv, 50 North Med Dr A-050, Salt Lake City, UT 84132 USAUniv Utah Hlth, Dept Pharm Serv, 50 North Med Dr A-050, Salt Lake City, UT 84132 USA
Lonardo, Nick
Tonna, Joseph
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机构:
Univ Utah Hlth, Div Cardiothorac Surg, Dept Surg, 50 North Med Dr, Salt Lake City, UT 84132 USA
Univ Utah Hlth, Dept Surg, Div Emergency Med, 50 North Med Dr, Salt Lake City, UT 84132 USAUniv Utah Hlth, Dept Pharm Serv, 50 North Med Dr A-050, Salt Lake City, UT 84132 USA