Clinical and molecular characterization of hidradenitis suppurativa: a practical framework for novel therapeutic targets

被引：4
|
作者：
Moltrasio, Chiara [1 ]
Tricarico, Paola Maura [2 ]
Moura, Ronald Rodrigues [2 ]
Brandao, Lucas [3 ]
Crovella, Sergio [4 ]
Marzano, Angelo Valerio [1 ,5 ,6 ,7 ]
机构：
[1] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Dermatol Unit, Milan, Italy
[2] IRCCS Burlo Garofolo, Inst Maternal & Child Hlth, Trieste, Italy
[3] Univ Fed Pernambuco, Ctr Med Sci, Dept Pathol, BR-50670901 Recife, Brazil
[4] Qatar Univ, Lab Anim Res Ctr LARC, Doha, Qatar
[5] Univ Milan, Dept Pathophysiol & Transplantat, Milan, Italy
[6] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Dermatol Unit, Via Pace 9, I-20122 Milan, Italy
[7] Univ Milan, Dept Pathophysiol & Transplantat, Via Pace 9, I-20122 Milan, Italy
来源：
DERMATOLOGY | 2023年 / 239卷 / 05期
关键词：
2D-3D cells and organoids models; Autoinflammatory skin diseases; Biomarkers discovery; Causative genetic variants and disrupted pathways; Genotype-phenotype correlation; Hidradenitis suppurativa; Syndromic forms; Tailored treatment;
D O I：
10.1159/000531496
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
N/A
引用
收藏
页码：836 / 839
页数：4
相关论文
共 50 条
  • [1] Novel Therapeutic Approaches and Targets for the Treatment of Hidradenitis Suppurativa
    Giuffrida, Roberta
    Cannavo, Serafinella Patrizia
    Coppola, Marialorena
    Guarneri, Claudio
    CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 2021, 22 (01) : 59 - 72
  • [2] Inflammasomes: emerging therapeutic targets in hidradenitis suppurativa?
    Campbell, Ciara
    Mayatra, Jay M.
    Neve, Ashish J.
    Fletcher, Jean M.
    Johnston, Daniel G. W.
    BRITISH JOURNAL OF DERMATOLOGY, 2024, 191 (05) : 670 - 679
  • [3] Comprehensive search for therapeutic targets and understanding of fibrosis in hidradenitis suppurativa
    Omine, T.
    Utsumi, D.
    Yamaguchi, S.
    Takahashi, K.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2023, 143 (05) : S175 - S175
  • [4] A Systematic Review of Promising Therapeutic Targets in Hidradenitis Suppurativa: A Critical Evaluation of Mechanistic and Clinical Relevance
    Frew, John W.
    Marzano, Angelo V.
    Wolk, Kerstin
    Join-Lambert, Olivier
    Alavi, Afsaneh
    Lowes, Michelle A.
    Piguet, Vincent
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2021, 141 (02) : 316 - +
  • [5] Demographic and Therapeutic Trends in Clinical Trials for Hidradenitis Suppurativa
    Mulligan, Kathleen
    O'Connell, Katie
    Ahmad, Areebah
    Kim, Lori
    Coleman, Madeline
    da Silva, Alexandra
    Dellavalle, Robert
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2023, 89 (03) : AB32 - AB32
  • [6] A comprehensive, patient-based approach to the clinical and molecular classification of complex, syndromic hidradenitis suppurativa phenotypes: a practical, translational framework
    Moltrasio, Chiara
    Genovese, Giovanni
    Crovella, Sergio
    Tricarico, Paola M.
    Boniotto, Michele
    Garcovich, Simone
    Marzano, Angelo V.
    EXPERIMENTAL DERMATOLOGY, 2021, 30 : 43 - 44
  • [7] Molecular characterization of hidradenitis suppurativa/acne inversa (HS)
    Zouboulis, C.
    Makrantonaki, E.
    Hossini, A.
    Bonitsis, N.
    da Costa, A.
    EXPERIMENTAL DERMATOLOGY, 2018, 27 : 13 - 13
  • [8] Metabolic syndrome and hidradenitis suppurativa: epidemiological, molecular, and therapeutic aspects
    Mintoff, Dillon
    Benhadou, Farida
    Pace, Nikolai P.
    Frew, John W.
    INTERNATIONAL JOURNAL OF DERMATOLOGY, 2022, 61 (10) : 1175 - 1186
  • [9] Impaired Molecular Mechanisms Contributing to Chronic Pain in Patients with Hidradenitis Suppurativa: Exploring Potential Biomarkers and Therapeutic Targets
    Radhakrishna, Uppala
    Kuracha, Murali R.
    Hamzavi, Iltefat
    Saiyed, Nazia
    Prajapati, Jignesh
    Rawal, Rakesh M.
    Uppala, Lavanya V.
    Damiani, Giovanni
    Ratnamala, Uppala
    Nath, Swapan K.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2025, 26 (03)
  • [10] Methylated miRNAs may serve as potential biomarkers and therapeutic targets for hidradenitis suppurativa
    Radhakrishna, U.
    Ratnamala, U.
    Jhala, D. D.
    Vadsaria, N.
    Patel, M.
    Uppala, L., V
    Vishweswaraiah, S.
    Vedangi, A.
    Saiyed, N.
    Damiani, G.
    Jemec, G. B. E.
    JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2022, 36 (11) : 2199 - 2213
12345