The tubulin structure, a quarter of a century later

被引:0
|
作者
Nogales, Eva [1 ,2 ,3 ]
机构
[1] Univ Calif Berkeley, Mol & Cell Biol Dept, Berkeley, CA 94720 USA
[2] Lawrence Berkeley Natl Lab, Mol Biophys & Integrated Bioimaging Div, Berkeley, CA 94720 USA
[3] Univ Calif Berkeley, Howard Hughes Med Inst, Berkeley, CA 94720 USA
关键词
Keith Kozminski; University of Virginia; ALPHA-BETA-TUBULIN; CRYSTAL-STRUCTURE; ACTIN; MODEL; ANGSTROM; DIMER;
D O I
10.1091/mbc.E23-01-0005
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
This retrospective on the 25th anniversary of the publication of the first structure of tubulin is shaped by my own personal experiences rather than being a strict and complete historical account of the event. It is a reflection on how working in science felt many years ago, on the struggles and the joys of reaching for the high-hanging fruit, and, ultimately, on how relevant or not our personal scientific contributions are to the broader scientific com- munity. Writing it brought back memories of my unique and sadly lost postdoctoral advisor Ken Downing, who dreamt of this structure and brought it to fruition against all odds.
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页码:1 / 4
页数:4
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