Nanotechnology-Based Nucleic Acid Vaccines for Treatment of Ovarian Cancer

被引：8
|
作者：
Gildiz, Simav [1 ]
Minko, Tamara [1 ,2 ]
机构：
[1] Rutgers State Univ, Dept Pharmaceut, Piscataway, NJ 08854 USA
[2] Rutgers State Univ, Rutgers Canc Inst New Jersey, Piscataway, NJ 08854 USA
来源：
PHARMACEUTICAL RESEARCH | 2023年 / 40卷 / 01期
基金：
美国国家卫生研究院;
关键词：
cancer; mRNA; nanoparticles; ovarian; vaccine; ORAL-CONTRACEPTIVE USE; EPITHELIAL OVARIAN; REPRODUCTIVE FACTORS; HEPATITIS-B; TALIMOGENE LAHERPAREPVEC; CALMETTE-GUERIN; BLADDER-CANCER; CELL CARCINOMA; FALLOPIAN-TUBE; BREAST-CANCER;
D O I：
10.1007/s11095-022-03434-4
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Anticancer vaccines represent a promising approach for effective treatment of cancer and along with recent advantages of nucleic acid-based vaccines for other diseases form a prospective and potentially efficacious direction of the research, development and clinical applications. Despite the ongoing several clinical trials of mRNA vaccines for the treatment of various types of cancer, to-date no cancer vaccines were approved by the US Food and Drug Administration. The present review analyzes and summarizes major approaches for treating of different forms of ovarian cancer including mRNA-based vaccines as well as nanotechnology-based approaches for their delivery.
引用
收藏
页码：123 / 144
页数：22
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