Mechanistic insights into the 'broken heart syndrome'

被引：0
|
作者：
Backs, Johannes [1 ]
机构：
[1] Heidelberg Univ, Inst Expt Cardiol, Heidelberg, Germany
来源：
NATURE CARDIOVASCULAR RESEARCH | 2023年 / 2卷 / 07期
关键词：
D O I：
10.1038/s44161-023-00309-8
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We established a mouse model that recapitulates the clinical symptoms of Takotsubo syndrome ('broken heart syndrome') and revealed a causal relationship between calcineurin-dependent cardiac inflammation and disease severity. Inhibition of calcineurin as a therapeutic approach is now entering a multi-center clinical trial.
引用
收藏
页码：613 / 614
页数：2
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