TARGETING A SHARED GLIOBLASTOMA CELL STATE THROUGH ADAPTIVE NATURAL KILLER CELLS AUGMENTED WITH TRISPECIFIC KILLER CELL ENGAGER (TRIKE) IMMUNE-MODULATOR AGAINST CD276

被引：0
|
作者：
Ning, Jianfang [1 ]
Davis, Zachary [1 ]
Zhu, Shan [1 ]
Miller, Jeffrey [1 ]
Chen, Clark [1 ]
机构：
[1] Univ Minnesota, Minneapolis, MN USA
来源：
NEURO-ONCOLOGY | 2023年 / 25卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
SURG-09
引用
收藏
页数：1
相关论文
共 18 条
  • [1] Trispecific killer engager 161519 enhances natural killer cell function and provides anti-tumor activity against CD19-positive cancers
    Cheng, Ying
    Zheng, Xiaodong
    Wang, Xuefu
    Chen, Yongyan
    Wei, Haiming
    Sun, Rui
    Tian, Zhigang
    Sun, Haoyu
    CANCER BIOLOGY & MEDICINE, 2020, 17 (04) : 1026 - 1038
  • [2] Trispecific killer engager 161519 enhances natural killer cell function and provides anti-tumor activity against CD19-positive cancers
    Ying Cheng
    Xiaodong Zheng
    Xuefu Wang
    Yongyan Chen
    Haiming Wei
    Rui Sun
    Zhigang Tian
    Haoyu Sun
    Cancer Biology & Medicine , 2020, (04) : 1026 - 1038
  • [3] Trispecific killer engager 161519 enhances natural killer cell function and provides anti-tumor activity against CD19-positive cancers
    Ying Cheng
    Xiaodong Zheng
    Xuefu Wang
    Yongyan Chen
    Haiming Wei
    Rui Sun
    Zhigang Tian
    Haoyu Sun
    Cancer Biology & Medicine, 2020, 17 (04) : 1026 - 1038
  • [4] CD16-IL15-CD33 Trispecific Killer Engager (TriKE) Overcomes Cancer-Induced Immune Suppression and Induces Natural Killer Cell-Mediated Control of MDS and AML Via Enhanced Killing Kinetics
    Felices, Martin
    Sarhan, Dhifaf
    Brandt, Ludwig
    Guldevall, Karolin
    McElmurry, Ron
    Lenvik, Alexander
    Chu, Sami
    Tolar, Jakub
    Taras, Elizabeth
    Spellman, Stephen R.
    Warlick, Erica D.
    Verneris, Michael R.
    Cooley, Sarah
    Weisdorf, Daniel
    Blazar, Bruce R.
    Onfelt, Bjorn
    Vallera, Dan
    Miller, Jeffrey S.
    BLOOD, 2016, 128 (22)
  • [5] GTB-5550 (cam16-IL15-camB7H3) trispecific killer engager (TriKE®) drives natural killer cell activation and antibody dependent cellular cytotoxicity against head and neck squamous cell carcinomas
    Khaw, Melissa
    Davis, Zachary
    Zorko, Nicholas
    Berk, Greg
    Choy, Gavin
    MacMillan, Margaret
    Felices, Martin
    Miller, Jeffrey S.
    CANCER RESEARCH, 2022, 82 (12)
  • [6] A regulatory loop among CD276, miR-29c-3p, and Myc exists in cancer cells against natural killer cell cytotoxicity
    Lee, Chin-Cheng
    Ho, Kuo-Hao
    Huang, Tzu-Wen
    Shih, Chwen-Ming
    Hsu, Shao-Yuan
    Liu, Ann-Jeng
    Chen, Ku-Chung
    LIFE SCIENCES, 2021, 277
  • [7] Targeting Natural Killer Cells to Acute Myeloid Leukemia In Vitro with a CD16 x 33 Bispecific Killer Cell Engager and ADAM17 Inhibition
    Wiernik, Andres
    Foley, Bree
    Zhang, Bin
    Verneris, Michael R.
    Warlick, Erica
    Gleason, Michelle K.
    Ross, Julie A.
    Luo, Xianghua
    Weisdorf, Daniel J.
    Walcheck, Bruce
    Vallera, Daniel A.
    Miller, Jeffrey S.
    CLINICAL CANCER RESEARCH, 2013, 19 (14) : 3844 - 3855
  • [8] Trispecific killer engager CD16xIL15xCD33 potently induces NK cell activation and cytotoxicity against neoplastic mast cells
    Yun, Hyun Don
    Felices, Martin
    Vallera, Daniel A.
    Hinderlie, Peter
    Cooley, Sarah
    Arock, Michel
    Gotlib, Jason
    Ustun, Celalettin
    Miller, Jeffrey S.
    BLOOD ADVANCES, 2018, 2 (13) : 1580 - 1584
  • [9] CD70 targeting bi-specific Natural Killer cell Engager (BIKE) eliminate acute myeloid leukemia cells
    Boy, M.
    Bratschi, H.
    Riether, C.
    Ochsenbein, A.
    SWISS MEDICAL WEEKLY, 2023, 153 : 5S - 6S
  • [10] CD16-IL15-CLEC12A Trispecific Killer Engager (TriKE) Drives NK Cell Expansion, Activation, and Antigen Specific Killing of Cancer Stem Cells in Acute Myeloid Leukemia
    Arvindam, Upasana Sunil
    van Hauten, Paulien
    Hallstrom, Caroline
    Vallera, Daniel A.
    Dolstra, Harry
    Miller, Jeffrey S.
    Felices, Martin
    BLOOD, 2018, 132
12