The Role of Extracellular Vesicles in Colorectal Cancer

被引：3
|
作者：
Xia, Yujian [1 ]
Yu, Chaoran [2 ]
Helwig, Ernest Johann [3 ]
Li, Yousheng [2 ]
机构：
[1] Soochow Univ, Affiliated Hosp 1, Dept Gen Surg, Suzhou, Jiangsu, Peoples R China
[2] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Dept Gen Surg, Sch Med, Shanghai, Peoples R China
[3] Huazhong Univ Sci & Technol, Tongji Med Coll, Wuhan, Peoples R China
来源：
TECHNOLOGY IN CANCER RESEARCH & TREATMENT | 2023年 / 22卷
关键词：
Colorectal cancer; extracellular vesicles (EVs); treatment; diagnosis; EXOSOMES; MICROENVIRONMENT; SECRETION; RELEVANCE; DELIVERY;
D O I：
10.1177/15330338231185008
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Extracellular vesicles (EVs) are a class of spherical vesicles that are produced by active secretion of cells and encapsulated by phospholipid bilayers. In recent years, numerous studies have shown that EVs play pivotal roles in the regulation of intercellular communication between colorectal cancer (CRC) cells and target cells, and can regulate the proliferation, metastasis, and infiltration of tumor cells by regulating the microenvironment of tumor cells. EVs carry specific molecular substances in source CRC cells and are expected to serve as new molecular markers for the detection of cancers. This review highlights the current state of research and progress of potentially incorporating EVs in the diagnosis and treatment of CRC.
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页数：6
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