Pemphigoid diseases in infancy and childhood. A review of the literature

Bullous pemphigoid is an autoimmune blistering disease that very ra-rely affects children. Clinical differences in locations of skin lesions led to the distinction of infantile versus childhood pemphigoid. Mucous membranes can be affected. The first-line therapy usually consists of topical or/and systemic glucocorticosteroids. Intravenous immunoglo-bulin infusions can be a valuable treatment option. Prognosis of infan-tile pemphigoid and childhood pemphigoid is good and the duration is often limited to one year with adequate treatment. The differential diagnosis of blisters should include: linear immunoglobulin A bullous disease of childhood, epidermolysis bullosa acquisita, bullous systemic lupus erythematosus, bullous scabies and childhood infectious diseases with blisters.