Acellular fish skin for wound healing

被引:15
|
作者
Esmaeili, Ali [1 ]
Biazar, Esmaeil [2 ]
Ebrahimi, Maryam [3 ]
Keshel, Saeed Heidari [1 ]
Kheilnezhad, Bahareh [4 ]
Landi, Farzaneh Saeedi [1 ]
机构
[1] Shahid Beheshti Univ Med Sci, Sch Adv Technol Med, Dept Tissue Engn & Appl Cell Sci, Tehran, Iran
[2] Islamic Azad Univ, Dept Biomed Engn, Tonekabon Branch, Tissue Engn Grp, Tonekabon, Iran
[3] Univ Tehran Med Sci, Sch Adv Technol Med, Dept Tissue Engn, Tehran, Iran
[4] Amirkabir Univ Technol, Dept Biomed Engn, Tehran, Iran
关键词
biological and physical & mechanical properties; decellularization; fish skin; in-vivo studies; wound healing; DERMAL MATRIX; CROSS-LINKING; TISSUE; DECELLULARIZATION; MANAGEMENT; GRAFTS;
D O I
10.1111/iwj.14158
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Fish skin grafting as a new skin substitute is currently being used in clinical applications. Acceleration of the wound healing, lack of disease transmission, and low cost of the production process can introduce fish skin as a potential alternative to other grafts. An appropriate decellularization process allows the design of 3D acellular scaffolds for skin regeneration without damaging the morphology and extracellular matrix content. Therefore, the role of decellularization processes is very important to maintain the properties of fish skin. In this review article, recent studies on various decellularization processes as well as biological, physical, and mechanical properties of fish skin and its applications with therapeutic effects in wound healing were investigated.
引用
收藏
页码:2924 / 2941
页数:18
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