Molecular docking and dynamics simulation of main protease of SARS-CoV-2 with naproxen derivative

被引：2
|
作者：
Hussein, Rageh K. [1 ]
Marashdeh, Mohammad [1 ]
El-Khayatt, Ahmed M. [1 ]
机构：
[1] Imam Mohammad Ibn Saud Islamic Univ IMSIU, Coll Sci, Dept Phys, Riyadh, Saudi Arabia
来源：
BIOINFORMATION | 2023年 / 19卷 / 04期
关键词：
Naproxen derivative; SARS-CoV-2; drug-likeness and ADMET properties; Molecular docking; Molecular dynamics;
D O I：
10.6026/97320630019358
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Naproxen is a well-known anti-inflammatory drug that is frequently used to relieve inflammation, stiffness, and swelling. Naproxen has previously demonstrated antiviral activity, particularly against the influenza-A virus. There have been previous studies regarding naproxen effect on SARS-CoV-2 infection. Therefore, it is of interest to document the molecular docking and dynamics simulation data of main protease of SARS-CoV-2 with naproxen derivative for further consideration.
引用
收藏
页码：358 / 361
页数：4
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