Infectious Diseases Evaluation of the Child With Suspected Hemophagocytic Lymphohistiocytosis

被引：0
|
作者：
Leon, Maria Deza [1 ,4 ]
Otto, William R. [1 ,2 ]
Danziger-Isakov, Lara [1 ,2 ]
Kumar, Ashish [2 ,3 ]
Huang, Felicia Scaggs [2 ]
机构：
[1] Cincinnati Childrens Hosp Med Ctr, Div Infect Dis, Cincinnati, OH USA
[2] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH USA
[3] Cincinnati Childrens Hosp Med Ctr, Div Bone Marrow Transplant & Immune Deficiency, Cincinnati, OH USA
[4] Cincinnati Childrens Hosp Med Ctr, 3333 Burnet Ave, Cincinnati, OH 45229 USA
来源：
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY | 2024年 / 13卷 / 03期
关键词：
cytokine storm; hemophagocytosis; HLH; infection; EXPRESSION; DIAGNOSIS; TLR9; VALIDATION; MECHANISMS; RESPONSES; PERFORIN; CELLS; SCORE; GENE;
D O I：
10.1093/jpids/piae007
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive and maladaptive inflammation. In this review, we discuss how the clinical and laboratory features of HLH overlap with infection and propose a diagnostic and treatment strategy to identify patients with infections mimicking HLH.
引用
收藏
页码：220 / 227
页数：8
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