Comparative Phtyochemical Analysis of Kanakasava, Kanakasava Distillate, and Kanakasava Nebulizer Solution using Gas Chromatography-mass Spectrometry (GC-MS)

Introduction: Kanakasava is the classical formulation known to have beneficial effects on bronchial asthma. This study deals with the objective to compare the phytochemicals present in Kanakasava, Kanakasava distillate, and Kanakasava nebulizer solution using gas chromatography-mass spectrometry (GC-MS) and to determine if Kanakasava nebulizer solution can be useful in managing respiratory diseases. Methods: Kanakasava, Kanakasava distillate and Kanakasava nebulizer solution were prepared accordingly and standard GC-MS analysis was performed on the samples. Results: The GC-MS analysis indicated the presence of 6, 13 and 10 important phytochemicals in Kanakasava, Kanakasava distillate and Kanakasava nebulizer solution respectively. Many chemicals acting on the respiratory system were found in all three forms of Kanakasava and some of the chemicals were having similar actions. Conclusion: Despite the fact that the phytochemicals found in the three of them differed due to molecular fragmentation during the whole process, the efficacy of the novel Kanakasava nebulizer solution remained unaffected.