Single-cell transcriptomic analysis uncovers intratumoral heterogeneity and drug-tolerant persister in ALK-rearranged lung adenocarcinoma

被引:2
|
作者
Kwok, Hoi-Hin [1 ]
Li, Huiyu [2 ]
Yang, Jiashuang [1 ]
Deng, Junyang [1 ]
Lee, Nerissa Chui-Mei [1 ]
Au, Timmy Wing-Kuk [3 ]
Sit, Alva Ko-Yung [3 ]
Hsin, Michael Kuan-Yew [3 ]
Ma, Stephanie Kwai-Yee [4 ]
Cheung, Lydia Wai-Ting [4 ]
Girard, Luc [2 ]
Fujimoto, Junya [5 ]
Wistuba, Ignacio Ivan [5 ]
Gao, Boning [2 ]
Minna, John Dorrance [2 ]
Lam, David Chi-Leung [1 ,6 ]
机构
[1] Univ Hong Kong, Li Ka Shing Fac Med, Dept Med, Hong Kong, Peoples R China
[2] Univ Texas Southwestern Med Ctr, Nancy B & Jake L Hamon Ctr Therapeut Oncol Res, Dallas, TX USA
[3] Queen Mary Hosp, Cardiothorac Surg Dept, Hong Kong, Peoples R China
[4] Univ Hong Kong, Li Ka Shing Fac Med, Sch Biomed Sci, Hong Kong, Peoples R China
[5] Univ Texas MD Anderson Canc Ctr, Dept Translat Mol Pathol, Div Pathol Lab Med, Houston, TX USA
[6] Univ Hong Kong, Li Ka Shing Fac Med, Dept Med, Hong Kong 999077, Peoples R China
基金
中国国家自然科学基金;
关键词
MIGRATION; GENE;
D O I
10.1002/cac2.12449
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:951 / 955
页数:5
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