Correlation of CDKN2A Status with MTAP: Association with Molecular Subtype and Clinical Outcomes of Muscle Invasive Urothelial Carcinoma

被引：0
|
作者：
Oberc, Alexander [1 ]
Olkhov-Mitsel, Ekaterina [2 ]
Slodkowska, Elzbieta [3 ]
Craddock, Kenneth [3 ]
Downes, Michelle [2 ]
机构：
[1] Univ Toronto, Toronto, ON, Canada
[2] Sunnybrook Hlth Sci Ctr, Toronto, ON, Canada
[3] Univ Toronto, Sunnybrook Hlth Sci Ctr, Toronto, ON, Canada
来源：
LABORATORY INVESTIGATION | 2023年 / 103卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
789
引用
收藏
页码：S782 / S783
页数：2
相关论文
共 43 条
  • [1] Correlation of MTAP Immunohistochemistry With CDKN2A Status and Clinicopathological Features in Meningiomas
    Sasaki, Sho
    Takeda, Maiko
    Fujii, Tomomi
    Morita, Kohei
    Ohbayashi, Chiho
    CANCER SCIENCE, 2023, 114 : 461 - 461
  • [2] Clinicopathologic assessment of MTAP status in muscle invasive urothelial carcinoma
    Olkhov-Mitsel, E.
    Slodkowska, E.
    Downes, M.
    VIRCHOWS ARCHIV, 2022, 481 (SUPPL 1) : S173 - S173
  • [3] MTAP protein status is highly concordant with CDKN2A fluorescent in situ hybridization and allows stratification of the luminal subtype in muscle-invasive bladder cancer
    Olkhov-Mitsel, Ekaterina
    Oberc, Alexander
    Craddock, Kenneth J.
    Sherman, Christopher
    Slodkowska, Elzbieta
    Downes, Michelle R.
    HISTOPATHOLOGY, 2025, 86 (03) : 352 - 364
  • [4] Molecular prognostication in grade 3 meningiomas and p16/MTAP immunohistochemistry for predicting CDKN2A/B status
    Tosefsky, Kira
    Martin, Karina Chornenka
    Rebchuk, Alexander D.
    Wang, Justin Z.
    Nassiri, Farshad
    Lum, Amy
    Zadeh, Gelareh
    Makarenko, Serge
    Yip, Stephen
    NEURO-ONCOLOGY ADVANCES, 2024, 6 (01)
  • [5] CDKN2A homozygous deletion is associated with muscle invasion in FGFR3-mutated urothelial bladder carcinoma
    Rebouissou, Sandra
    Herault, Aurelie
    Letouze, Eric
    Neuzillet, Yann
    Laplanche, Agnes
    Ofualuka, Karina
    Maille, Pascale
    Leroy, Karen
    Riou, Audrey
    Lepage, May-Linda
    Vordos, Dimitri
    de la Taille, Alexandre
    Denoux, Yves
    Sibony, Mathilde
    Guyon, Frederic
    Lebret, Thierry
    Benhamou, Simone
    Allory, Yves
    Radvanyi, Francois
    JOURNAL OF PATHOLOGY, 2012, 227 (03): : 315 - 324
  • [6] Utility of methylthioadenosine phosphorylase (MTAP) immunohistochemistry in malignant pleural mesothelioma: correlation with CDKN2A genomic status and inter-assay agreement
    Zhang, Y. Z.
    Hughes, J.
    Nastase, A.
    Mandal, A.
    Brambilla, C.
    Rice, A.
    Robertus, J. L.
    Cookson, W. O.
    Moffatt, M. F.
    Nicholson, A. G.
    VIRCHOWS ARCHIV, 2020, 477 : S24 - S24
  • [7] Association of Peripheral Blood RASSF1A and CDKN2A Methylation Status with Smoking Behaviour in Nasopharyngeal Carcinoma
    Risanti, Erika Diana
    Kurniawan, Aditya
    Wahyuningsih, Laila
    Dwianingsih, Ery Kus
    Rinonce, Hanggoro Tri
    Fachiroh, Jajah
    INDONESIAN BIOMEDICAL JOURNAL, 2018, 10 (02): : 123 - 127
  • [8] ASSOCIATION OF HER2 STATUS WITH CLINICOPATHOLOGIC OUTCOMES IN MICROPAPILLARY UROTHELIAL CARCINOMA
    Schneider, Steven
    Sukov, William
    Frank, Igor
    Boorjian, Stephen
    Tarrell, Robert
    Thapa, Prabin
    Cheville, John
    JOURNAL OF UROLOGY, 2013, 189 (04): : E160 - E160
  • [9] Micropapillary urothelial carcinoma: evaluation of HER2 status and immunohistochemical characterization of the molecular subtype
    Zinnall, Ulrike
    Weyerer, Veronika
    Comperat, Eva
    Camparo, Philippe
    Gaisa, Nadine T.
    Knuechel-Clarke, Ruth
    Perren, Aurel
    Lugli, Alessandro
    Toma, Marieta
    Baretton, Gustavo
    Kristiansen, Glen
    Wirtz, Ralph M.
    Cheng, Liang
    Wullich, Bernd
    Stoehr, Robert
    Hartmann, Arndt
    Bertz, Simone
    HUMAN PATHOLOGY, 2018, 80 : 55 - 64
  • [10] Comprehensive analysis of CDKN2A status in microdissected urothelial cell carcinoma reveals potential haploinsufficiency, a high frequency of homozygous co-deletion and associations with clinical phenotype
    Chapman, EJ
    Harnden, P
    Chambers, P
    Johnston, C
    Knowles, MA
    CLINICAL CANCER RESEARCH, 2005, 11 (16) : 5740 - 5747
12345