Designer bugs as cancer drugs? Skin microbiota can be engineered to induce antitumor T cells

被引:1
|
作者
Sajjath, Sairaj M. [1 ]
Gola, Anita [1 ]
Fuchs, Elaine [1 ]
机构
[1] Rockefeller Univ, Howard Hughes Med Inst, Robin Chemers Neustein Lab Mammalian Cell Biol & D, New York, NY 10065 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1126/science.adh3884
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:132 / 133
页数:2
相关论文
共 50 条
  • [1] Engineered skin bacteria induce antitumor T cell responses against melanoma
    Chen, Y. Erin
    Bousbaine, Djenet
    Veinbachs, Alessandra
    Atabakhsh, Katayoon
    Dimas, Alex
    Yu, Victor K.
    Zhao, Aishan
    Enright, Nora J.
    Nagashima, Kazuki
    Belkaid, Yasmine
    Fischbach, Michael A.
    [J]. SCIENCE, 2023, 380 (6641) : 203 - 210
  • [2] Microbiota: Baby bugs can't stop the thugs
    Bordon Y.
    [J]. Nature Reviews Immunology, 2017, 17 (8) : 467 - 467
  • [3] Bugs as Drugs: Understanding the Linkage between Gut Microbiota and Cancer Treatment
    Rana, Dhwani
    Salave, Sagar
    Perla, Akhil
    Nadkarni, Akanksha
    Kolhe, Shital
    Jindal, Anil B.
    Mandoli, Amit
    Dwivedi, Pradeep
    Benival, Derajram
    [J]. CURRENT DRUG TARGETS, 2022, 23 (09) : 869 - 888
  • [4] Designer T cells in prostate cancer
    Day-Webb, Robert
    [J]. EUROPEAN JOURNAL OF CANCER, 2009, 45 (09) : 1528 - 1528
  • [5] TCR-engineered iNKT cells induce robust antitumor response by dual targeting cancer and suppressive myeloid cells
    Delfanti, Gloria
    Cortesi, Filippo
    Perini, Alessandra
    Antonini, Gaia
    Azzimonti, Laura
    de Lalla, Claudia
    Garavaglia, Claudio
    Squadrito, Mario L.
    Fedeli, Maya
    Consonni, Michela
    Sesana, Silvia
    Re, Francesca
    Shen, Haifa
    Dellabona, Paolo
    Casorati, Giulia
    [J]. SCIENCE IMMUNOLOGY, 2022, 8 (90)
  • [6] Engineered T cells can fight malignant T cells
    Stauss, Hans J.
    [J]. BLOOD, 2015, 126 (08) : 927 - 928
  • [7] TCR-Engineered, Customized, Antitumor T Cells for Cancer Immunotherapy: Advantages and Limitations
    Chhabra, Arvind
    [J]. THESCIENTIFICWORLDJOURNAL, 2011, 11 : 121 - 129
  • [8] Bugs, drugs, and cancer: can the microbiome be a potential therapeutic target for cancer management?
    Chen, Biying
    Du, Guangye
    Guo, Jiahui
    Zhang, Yanjie
    [J]. DRUG DISCOVERY TODAY, 2019, 24 (04) : 1000 - 1009
  • [9] Specialized Antitumor Functions for Skin γδ T Cells
    Havran, Wendy L.
    [J]. JOURNAL OF IMMUNOLOGY, 2018, 200 (09): : 3029 - 3030
  • [10] Adoptive cancer immunotherapy using genetically engineered designer T-cells: First steps into the clinic
    Eshhar, Zelig
    [J]. CURRENT OPINION IN MOLECULAR THERAPEUTICS, 2010, 12 (01) : 55 - 63