Comparison of Diagnostic Mammography- Guided Biopsy and Digital Breast Tomosynthesis- Guided Biopsy of Suspicious Breast Calcifications: Results in 1354 Biopsies

被引:4
|
作者
Budovec, Joseph J. [1 ]
Mautz, Alan [2 ]
机构
[1] Med Coll Wisconsin, Milwaukee, WI 53226 USA
[2] Northern Light AR Gould Hosp, Presque Isle, ME USA
关键词
biopsy; calcifications; digital breast tomosynthesis guided; radiation; stereotactic guided;
D O I
10.2214/AJR.22.28320
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
BACKGROUND. Studies have shown improved targeting and sampling of noncalcified lesions (asymmetries, masses, and architectural distortion) with digital breast tomosynthesis (DBT)-guided biopsy in comparison with digital mammography (DM)-guided stereotactic biopsy. Literature that compares the two techniques specifically for sampling calcifications has been scarce. OBJECTIVE. The purpose of this study was to compare the performance and outcomes of DM- and DBT-guided biopsy of suspicious calcifications. METHODS. This retrospective study included 1310 patients (mean age, 58 ± 12 [SD] years) who underwent a total of 1354 9-gauge vacuum-assisted core biopsies of suspicious calcifications performed at a single institution from May 22, 2017, to December 31, 2021. The decision to use a DM-guided or DBT-guided technique was made at the discretion of the radiologist performing the biopsy. Procedure time, the number of exposures during the procedure, and the histopathologic outcomes were recorded. The two techniques were compared using a two-sample t test for continuous variables and a chi-square test for categoric variables. Additional tests were performed using generalized estimating equations to control for the effect of the individual radiologist performing the biopsy. RESULTS. A total of 348 (26%) biopsies used DM guidance, and 1006 (74%) used DBT guidance. The mean procedure time was significantly lower for DBT-guided biopsy (14.9 ± 8.0 [SD] minutes) than for DM-guided biopsy (24.7 ± 14.3 minutes) (p < .001). The mean number of exposures was significantly lower for DBT-guided biopsy (4.1 ± 1.0 [SD] exposures) than for DM-guided biopsy (9.1 ± 3.3 exposures) (p < .001). The differences in procedure time and number of exposures remained significant (both p < .001) when controlling for the effect of the radiologist performing the biopsy. There were no significant differences (all p > .05) between DM-guided and DBT-guided biopsy in terms of the malignancy rate on initial biopsy (20% vs 19%), the rate of high-risk lesion upgrading (14% vs 22%), or the final malignancy rate (23% vs 22%). CONCLUSION. DBT-guided biopsy of suspicious calcifications can be performed with shorter procedure time and fewer exposures compared with DM-guided biopsy, without a significant difference in rates of malignancy or high-risk lesion upgrading. CLINICAL IMPACT. The use of a DBT-guided, rather than a DM-guided, biopsy technique for suspicious calcifications can potentially reduce patient discomfort and radiation exposure without affecting clinical outcomes. © 2023 American Roentgen Ray Society. All rights reserved.
引用
收藏
页码:223 / 223
页数:1
相关论文
共 50 条
  • [1] Digital breast tomosynthesis (DBT)-guided biopsy of calcifications: pearls and pitfalls
    Choudhery, Sadia
    Anderson, Tara
    Valencia, Elizabeth
    [J]. CLINICAL IMAGING, 2021, 72 : 83 - 90
  • [2] Digital breast tomosynthesis-guided biopsy results and complications
    Weinfurtner, R.
    Carter, T.
    [J]. BREAST, 2019, 44 : S43 - S43
  • [3] Digital Mammography Stereotactic Biopsy versus Digital Breast Tomosynthesis-guided Biopsy: Differences in Biopsy Targets, Pathologic Results, and Discordance Rates
    Rochat, Cleo J.
    Baird, Grayson L.
    Lourenco, Ana P.
    [J]. RADIOLOGY, 2020, 294 (03) : 518 - 527
  • [4] Digital breast tomosynthesis-guided vacuum-assisted biopsy of suspicious calcifications at different sites within one breast: Is biopsy of more than one location needed?
    Bode, Maike
    Huck, Luisa Charlotte
    Raaff, Vanessa
    Hitpass, Lea
    Braunschweig, Till
    Nebelung, Sven
    Kuhl, Christiane Katharina
    [J]. EUROPEAN JOURNAL OF RADIOLOGY, 2022, 154
  • [5] Diagnostic Performance of Digital Breast Tomosynthesis for Breast Suspicious Calcifications From Various Populations: A Comparison With Full-field Digital Mammography
    Li, Juntao
    Zhang, Hengwei
    Jiang, Hui
    Guo, Xuhui
    Zhang, Yinli
    Qi, Dan
    Guan, Jitian
    Liu, Zhenzhen
    Wu, Erxi
    Luo, Suxia
    [J]. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2019, 17 : 82 - 89
  • [6] Clinical Performance of the Tomosynthesis Guided Breast Biopsy
    Wang, Xiaoqin
    Canan, Arzu
    Patel, Shrujal
    Chen, Li
    Gibbs, Richard
    Szabunio, Margaret
    [J]. 14TH INTERNATIONAL WORKSHOP ON BREAST IMAGING (IWBI 2018), 2018, 10718
  • [7] Diagnostic Accuracy of Image Guided Breast Biopsies: Comparison of Traditional Stereotactic Biopsy and the Brevera Biopsy System
    Barnes, Spencer
    McMurtry, Valarie
    Goold, Eric
    Factor, Rachel
    Mahlow, Jonathon
    [J]. LABORATORY INVESTIGATION, 2023, 103 (03) : S96 - S96
  • [8] Implementation of Upright Digital Breast Tomosynthesis-guided Stereotactic Biopsy
    Omofoye, Toma S.
    Martaindale, Sarah
    Teichgraeber, Davis C.
    Parikh, Jay R.
    [J]. ACADEMIC RADIOLOGY, 2017, 24 (11) : 1451 - 1455
  • [9] Sonographically-guided vacuum-assisted biopsy with digital mammography-guided skin marking of suspicious breast microcalcifications: comparison of outcomes with stereotactic biopsy in Asian women
    Hahn, Soo Yeon
    Shin, Jung Hee
    Han, Boo-Kyung
    Ko, Eun Young
    [J]. ACTA RADIOLOGICA, 2011, 52 (01) : 29 - 34
  • [10] Positron Emission Mammography (PEM) Diagnostic Imaging and Guided Breast Biopsy
    Mueller, F. H. H.
    Hentschel, M.
    Weikel, W.
    Schmidt, D.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2012, 39 : S295 - S295