Distal Chronic Inflammatory Demyelinating Polyneuropathy Following COVID-19 Vaccination in a Patient with Solitary Plasmacytoma: A Case Report and Literature Review

We herein report a rare case of distal chronic inflammatory demyelinating polyneuropathy (CIDP) follow-ing coronavirus disease 2019 (COVID-19) vaccination. A 39-year-old woman with a solitary plasmacytoma developed general weakness 7 days after receiving the second dose of the Pfizer-BioNTech COVID-19 vac-cine, which had progressed for 3 months. A neurological examination revealed limb weakness with areflexia. Serological tests identified the presence of IgG antibodies against anti-GM1 and anti-GM2 gangliosides. Comprehensive evaluations met the criteria of distal CIDP. Intravenous immunoglobulin, intravenous methyl-prednisolone, oral prednisolone, and plasma exchange were administered, and she gradually improved. Physi-cians should be aware of CIDP as a rare complication of COVID-19 vaccination.