Robustness of closed-loop glucose control systems

被引：0

作者：

Wycilok, Artur ^{[1
]}

Mieja, Jaroslaw ^{[1
]}

机构：

[1] Silesian Tech Univ, Dept Biol & Syst Engn, Gliwice, Poland

来源：

ARCHIVES OF CONTROL SCIENCES | 2023年 / 33卷 / 03期

关键词：

artificial pancreas; closed-loop control; insulin pump; type; 1; diabetes; ARTIFICIAL PANCREAS; INSULIN DELIVERY; EXERCISE; MODEL;

D O I：

10.24425/acs.2023.146964

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

The main purpose of this work is to provide an extensive, simulation-based comparison of robustness of PID and MPC algorithms in control of blood glucose levels in patients with type 1 diabetes and thus answer the question of their safety. Cohort testing, with 1000 simulated, randomized patients allowed to analyze specific control quality indicators, such as number of hypoglycemic events, and length of hypo-and hyperglycemia periods. Results show that both algorithms provide a reasonable safety level, taking into account natural changes of patients' physiological parameters. At the same time, we point out drawbacks of each solution, as well as general problems arising in close-loop control of blood glucose level.

引用

页码：681 / 705

页数：25

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