Trichonafurin A: a New ?-Lactone Compound from the Marine- Derived Fungus Trichoderma atroviride ZW-7

被引：1
|
作者：
Zhai, Lu-Di [1 ]
Gao, Wei [1 ]
Liu, Li-Ting [1 ]
Zhang, Ke [1 ]
Zhang, De-Liang [1 ]
机构：
[1] Qingdao Hosp Tradit Chinese Med, Qingdao Hiser Hosp, Qingdao 266033, Peoples R China
来源：
RECORDS OF NATURAL PRODUCTS | 2023年
关键词：
Trichoderma atroviride; secondary metabolites; cytotoxic activity; 2023 ACG Publications; All rights reserved;
D O I：
10.25135/rnp.388.2302.2714
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A new gamma-lactone compound, trichonafurin A (1), was obtained from the culture of Trichoderma atroviride ZW-7, an endophyte of the marine brown alga Sargassum thunbergii. Its structure was unambiguously assigned by detailed interpretation of 1D/2D NMR and HRESIMS data. Trichonafurin A (1) exhibited moderate cytotoxicity against HeLa and HepG2 cell lines with IC50 values of 20.2 and 32.1 mu M, respectively.
引用
收藏
页码：721 / 725
页数：5
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