Two New Phloroglucinol Derivatives from Syzygium fluviatile

被引：0
|
作者：
Zhang, Ding-Li [1 ]
Hu, Yi-Kao [1 ]
He, Yuan-Biao [1 ]
Zhao, Yong [1 ]
机构：
[1] Yunnan Normal Univ, Fac Chem & Chem Engn, Juxian St, Kunming 650500, Yunnan, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2023年 / 59卷 / 05期
关键词：
Syzygium fluviatile; phloroglucinol; alpha-glucosidase;
D O I：
10.1007/s10600-023-04132-2
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Two new phloroglucinol derivatives were isolated from the leaves of Syzygium fluviatile. The structures were elucidated as (Z,Z,Z)-1-(2,4-dihydroxy-6-methoxyphenyl)-octadeca-9,12,15-trien-1-one (1) and (Z,Z)-1-(5-methyl-2,4-dihydroxy-6-methoxyphenyl)-octadeca-9,12-dien-1-one (2) by means of extensive spectroscopic analyses including HR-ESI-MS and NMR spectra. Among them, compound 1 exhibited significant inhibitory activity against alpha-glucosidase with an IC50 value of 3.63 mu M.
引用
收藏
页码：848 / 851
页数：4
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