Combining polyp diameter and polyp-to-bile ratio by dynamic contrast-enhanced CT scanning can improve the diagnostic specificity of gallbladder neoplastic polyps

被引：3

作者：

Li, Qiwei ^{[1
]}

Xu, Sunwang ^{[2
]}

Yuan, Zhiqing ^{[1
]}

Zhang, Yunhe ^{[3
]}

Lu, Qing ^{[4
]}

Qian, Lijun ^{[4
]}

Xu, Jianrong ^{[4
]}

Song, Yanyan ^{[5
]}

Zhao, Ling ^{[6
]}

Chen, Tao ^{[2
]}

机构：

[1] Shanghai Jiao Tong Univ, Renji Hosp, Sch Med, Dept Gen Surg, Shanghai, Peoples R China

[2] Shanghai Jiao Tong Univ, Renji Hosp, Sch Med, Dept Biliary Pancreat Surg, Shanghai, Peoples R China

[3] Tongji Univ, Shanghai East Hosp, Dept Crit Care Med, Sch Med, Shanghai, Peoples R China

[4] Shanghai Jiao Tong Univ, Renji Hosp, Sch Med, Dept Radiol, Shanghai, Peoples R China

[5] Shanghai Jiao Tong Univ, Clin Res Inst, Dept Biostat, Sch Med, Shanghai, Peoples R China

[6] Shanghai Jiao Tong Univ, Renji Hosp, Sch Med, Dept Pathol, Shanghai, Peoples R China

来源：

JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES | 2023年 / 30卷 / 07期

关键词：

cholesterol polyp; contrast-enhanced CT; gallbladder polypoid lesions; neoplastic polyp; polyp-to-bile ratio; RISK-FACTORS; LESIONS; MANAGEMENT; PREVALENCE; CM;

D O I：

10.1002/jhbp.1300

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Objective:This study aimed to distinguish between cholesterol and neoplastic gallbladder polyps using dynamic contrast-enhanced CT. Methods:The dataset retrospectively comprised 222 cases, including 106 cases of cholesterol polyps and 116 cases of neoplastic polyps (59 adenoma and 57 adenocarcinoma). The perception and Hounsfield units of the polyps and gallbladder bile were assessed by contrast-enhanced CT, and the polyp-to-bile ratio (PBR) was calculated. Receiver operating characteristic (ROC) curves and area under the curve analyses were used to assess the diagnostic value of the diameter and PBR for neoplastic polyps. Results:The diameter of cholesterol polyps was significantly smaller than that of neoplastic polyps. The proportion of perceived cholesterol polyps in the plain and arterial phases of CT were significantly lower than those of neoplastic polyps (p < .001). On the contrary, the CT values of gallbladder bile of cholesterol polyps were always significantly higher than those of neoplastic polyps (p < .001). The median PBR values of cholesterol polyps were significantly lower than those of neoplastic polyps (p <= .001). ROC analysis showed that diameter and a plain phase PRB had better diagnostic value for neoplastic polyps. Polyp diameter >= 11.95 mm and the plain phase PBR & GE;1.48 were the optimal cut-off values for diagnosis of neoplastic polyps. Combining a diameter >= 12 mm and a PBR in the plain phase >= 1.48 further improved neoplastic polyp diagnostic specificity and positive likelihood ratio (10.453). Conclusions:Polyp-to-bile ratio in contrast-enhanced CT scanning is a new and convenient index for identifying cholesterol and neoplastic gallbladder polyps.

引用

页码：904 / 913

页数：10