Time without Transfusion Reliance or Anemia Worsening: A Novel Method for Integrating Transfusion Dependence, Anemia, and Survival with Myelofibrosis Therapies Based on the Phase 3 Simplify-1 and Simplify-2 Trials

被引:0
|
作者
Mesa, Ruben A. [1 ]
Talpaz, Moshe [2 ]
Mazerolle, Flora [3 ]
Gorsh, Boris [4 ]
M'Hari, Manal [3 ]
Regnault, Antoine [3 ]
Ellis, Catherine [4 ]
Wang, Zhaohui [4 ]
Purser, Molly [4 ]
Liu, Tom [4 ]
Strouse, Bryan [4 ]
Patnaik, Dwaipayan [5 ]
机构
[1] Atrium Hlth Wake Forest Baptist, Comprehens Canc Ctr, Winston Salem, NC USA
[2] Univ Michigan, Comprehens Canc Ctr, Ann Arbor, MI USA
[3] Modus Outcomes, Lyon, France
[4] GSK Plc, Collegeville, PA USA
[5] GSK, Baar, Switzerland
关键词
D O I
10.1182/blood-2023-177784
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:4
相关论文
共 7 条
  • [1] Overall survival in the SIMPLIFY-1 and SIMPLIFY-2 phase 3 trials of momelotinib in patients with myelofibrosis
    Mesa, Ruben
    Harrison, Claire
    Oh, Stephen T.
    Gerds, Aaron T.
    Gupta, Vikas
    Catalano, John
    Cervantes, Francisco
    Devos, Timothy
    Hus, Marek
    Kiladjian, Jean-Jacques
    Lech-Maranda, Ewa
    McLornan, Donal
    Vannucchi, Alessandro M.
    Platzbecker, Uwe
    Huang, Mei
    Strouse, Bryan
    Klencke, Barbara
    Verstovsek, Srdan
    LEUKEMIA, 2022, 36 (09) : 2261 - 2268
  • [2] Overall survival in the SIMPLIFY-1 and SIMPLIFY-2 phase 3 trials of momelotinib in patients with myelofibrosis
    Ruben Mesa
    Claire Harrison
    Stephen T. Oh
    Aaron T. Gerds
    Vikas Gupta
    John Catalano
    Francisco Cervantes
    Timothy Devos
    Marek Hus
    Jean-Jacques Kiladjian
    Ewa Lech-Maranda
    Donal McLornan
    Alessandro M. Vannucchi
    Uwe Platzbecker
    Mei Huang
    Bryan Strouse
    Barbara Klencke
    Srdan Verstovsek
    Leukemia, 2022, 36 : 2261 - 2268
  • [3] Transfusion-Related Cost and Time Burden Offsets in Patients with Myelofibrosis Treated with Momelotinib in the SIMPLIFY-1 and SIMPLIFY-2 Trials
    Masarova, Lucia
    Liu, Tom
    Fillbrunn, Mirko
    Li, Weilong
    Sajeev, Gautam
    Rao, Sumati
    Gorsh, Boris
    Signorovitch, James
    CANCERS, 2024, 16 (23)
  • [4] Red Blood Cell Transfusion Independence Status Is an Independent Predictor of Survival: A Post Hoc Time-Dependent Analysis of the Phase 3 Simplify-1, Simplify-2, and Momentum Trials
    Gupta, Vikas
    Harrison, Claire N.
    Gorsh, Boris
    Patel, Bharat
    Wang, Zhaohui
    Purser, Molly
    Ellis, Catherine
    Strouse, Bryan
    Patnaik, Dwaipayan
    Kawashima, Jun
    Mesa, Ruben A.
    BLOOD, 2023, 142
  • [5] Transfusion Intensity Over Time in Patients From the Phase 3 SIMPLIFY-1 and MOMENTUM Trials of Momelotinib
    Mesa, Ruben
    Perkins, Andrew
    Goh, Yeow Tee
    Fox, Maria Laura
    McLornan, Donal
    Palmer, Jeanne
    Foltz, Lynda
    Vannucchi, Alessandro
    Koschmieder, Steffen
    Passamonti, Francesco
    Lee, Sung Eun
    Kawashima, Jun
    Strouse, Bryan
    Carreras, Francisco Gonzalez
    Oh, Stephen
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2024, 24 : S411 - S411
  • [6] Longitudinal Assessment of Transfusion Intensity in Patients with JAK Inhibitor-Naive or -Experienced Myelofibrosis Treated with Momelotinib in the Phase 3 SIMPLIFY-1 and MOMENTUM Trials
    Mesa, Ruben
    Griesshammer, Martin
    Perkins, Andrew
    Goh, Yeow Tee
    Fox, Maria Laura
    Mclornan, Donal
    Palmer, Jeanne
    Foltz, Lynda
    Vannucchi, Alessandro M.
    Koschmieder, Steffen
    Passamonti, Francesco
    Lee, Sung Eun
    Kawashima, Jun
    Strouse, Bryan
    Carreras, Francisco Gonzalez
    Oh, Stephen
    ONCOLOGY RESEARCH AND TREATMENT, 2024, 47 : 122 - 122
  • [7] Longitudinal Assessment of Transfusion Intensity in Patients with JAK Inhibitor-Naive or Experienced Myelofibrosis Treated with Momelotinib in the Phase 3 Simplify-1 and Momentum Trials
    Mesa, Ruben A.
    Perkins, Andrew C.
    Goh, Yeow Tee
    Fox, Maria Laura
    McLornan, Donal P.
    Palmer, Jeanne
    Foltz, Lynda
    Vannucchi, Alessandro Maria
    Koschmieder, Steffen
    Passamonti, Francesco
    Lee, Sung-Eun
    Kawashima, Jun
    Strouse, Bryan
    Carreras, Francisco Gonzalez
    Oh, Stephen T.
    BLOOD, 2023, 142