Appetite Predicts Long-Term Clinical Outcomes in Patients with Acute Myocardial Infarction

被引:0
|
作者
Ishibashi, Shun [1 ]
Sakakura, Kenichi [1 ]
Ikeda, Tomoya [1 ]
Taniguchi, Yousuke [1 ]
Jinnouchi, Hiroyuki [1 ]
Tsukui, Takunori [1 ]
Watanabe, Yusuke [1 ]
Hatori, Masashi [1 ]
Yamamoto, Kei [1 ]
Seguchi, Masaru [1 ]
Fujita, Hideo [1 ]
机构
[1] Jichi Med Univ, Saitama Med Ctr, Div Cardiovasc Med, 1-847 Amanuma, Saitama 3308503, Japan
关键词
percutaneous coronary intervention; acute myocardial infarction; appetite; major adverse cardiac events; 6-MONTH OUTCOMES; CULPRIT LESION; ELEVATION; REGISTRY; EVENTS;
D O I
10.3390/jcm12196134
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Recently, the nutritional status of patients has drawn attention in an aging society. Early studies have reported that nutritional status is related to long-term outcomes in patients with acute myocardial infarction (AMI). However, it is not necessarily simple to evaluate the nutritional status of patients with AMI. We hypothesized that appetite before discharge can be a predictor for long-term adverse cardiovascular events in patients with AMI. This retrospective study aimed to investigate whether appetite is related to long-term adverse outcomes in patients with AMI. Methods: This study included 1006 patients with AMI, and divided them into the good appetite group (n = 860) and the poor appetite group (n = 146) according to the percentage of the dietary intake on the day before discharge. Major adverse cardiac events (MACE), which were defined as a composite of all-cause death, non-fatal MI, and re-admission for heart failure, were set as the primary outcome. Results: The median follow-up duration was 996 days, and a total of 243 MACE was observed during the study period. MACE was more frequently observed in the poor appetite group than in the good appetite group (42.5% versus 21.0%, p < 0.001). In the multivariate COX hazard model, poor appetite was significantly associated with MACE (Hazard ratio 1.698, 95% confidence interval 1.243-2.319, p < 0.001) after controlling for multiple confounding factors. Conclusion: Appetite at the time of discharge was significantly associated with long-term clinical outcomes in patients with AMI. Patients with poor appetite should be carefully followed up after discharge from AMI.
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页数:11
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