Childhood adversity represents a robust risk factor for the development of harmful substance use. Although a range of empirical studies have examined the consequences of multiple forms of adversity (i.e., childhood maltreatment, parental alcohol use disorder [AUD]), there is a dearth of information on the relative effects of each form of adversity when considered simultaneously. The current study utilizes structural equation modeling to investigate three unique and amplifying pathways from parental AUD and maltreatment exposure to offspring alcohol use as emerging adults: (1) childhood externalizing symptomatology, (2) internalizing symptomatology, and (3) affiliation with substance-using peers and siblings. Participants (N = 422) were drawn from a longitudinal follow-up study of emerging adults who participated in a research summer camp program as children. Wave 1 of the study included 674 school-aged children with and without maltreatment histories. Results indicated that chronic maltreatment, over and above the effect of parent AUD, was uniquely associated with greater childhood conduct problems and depressive symptomatology. Mother alcohol dependence was uniquely associated with greater affiliation with substance-using peers and siblings, which in turn predicted greater alcohol use as emerging adults. Results support peer and sibling affiliation as a key mechanism in the intergenerational transmission of substance use between mothers and offspring.
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Virginia Commonwealth Univ, Dept Psychol, Box 2018, Richmond, VA 23284 USA
Virginia Commonwealth Univ, Virginia Inst Psychiat & Behav Genet, Richmond, VA USAVirginia Commonwealth Univ, Dept Psychol, Box 2018, Richmond, VA 23284 USA
Salvatore, Jessica E.
Lonn, Sara Larsson
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Lund Univ, Ctr Primal Hlth Care Res, Malmo, SwedenVirginia Commonwealth Univ, Dept Psychol, Box 2018, Richmond, VA 23284 USA
Lonn, Sara Larsson
Long, Elizabeth C.
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Virginia Commonwealth Univ, Inst Drug & Alcohol Studies, Richmond, VA USAVirginia Commonwealth Univ, Dept Psychol, Box 2018, Richmond, VA 23284 USA
Long, Elizabeth C.
Sundquist, Jan
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Lund Univ, Ctr Primal Hlth Care Res, Malmo, SwedenVirginia Commonwealth Univ, Dept Psychol, Box 2018, Richmond, VA 23284 USA
Sundquist, Jan
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Kendler, Kenneth S.
Sundquist, Kristina
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Lund Univ, Ctr Primal Hlth Care Res, Malmo, SwedenVirginia Commonwealth Univ, Dept Psychol, Box 2018, Richmond, VA 23284 USA
Sundquist, Kristina
Edwards, Alexis C.
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Virginia Commonwealth Univ, Virginia Inst Psychiat & Behav Genet, Richmond, VA USAVirginia Commonwealth Univ, Dept Psychol, Box 2018, Richmond, VA 23284 USA
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Univ Bristol, Sch Social & Community Med, Bristol, Avon, EnglandUniv Bristol, Sch Social & Community Med, Bristol, Avon, England
Mahedy, Liam
Hammerton, Gemma
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Univ Bristol, Sch Social & Community Med, Bristol, Avon, EnglandUniv Bristol, Sch Social & Community Med, Bristol, Avon, England
Hammerton, Gemma
Teyhan, Alison
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Univ Bristol, Sch Social & Community Med, Bristol, Avon, EnglandUniv Bristol, Sch Social & Community Med, Bristol, Avon, England
Teyhan, Alison
Edwards, Alexis C.
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Virginia Commonwealth Univ, Dept Psychiat, Virginia Inst Psychiat & Behav Genet, Richmond, VA USA
Virginia Commonwealth Univ, Sch Med, Virginia Inst Psychiat & Behav Genet, Richmond, VA USAUniv Bristol, Sch Social & Community Med, Bristol, Avon, England
Edwards, Alexis C.
Kendler, Kenneth S.
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Virginia Commonwealth Univ, Dept Psychiat, Virginia Inst Psychiat & Behav Genet, Richmond, VA USA
Virginia Commonwealth Univ, Sch Med, Virginia Inst Psychiat & Behav Genet, Richmond, VA USAUniv Bristol, Sch Social & Community Med, Bristol, Avon, England
Kendler, Kenneth S.
Moore, Simon C.
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Cardiff Univ, Sch Dent, Coll Biomed & Life Sci, Cardiff, S Glam, WalesUniv Bristol, Sch Social & Community Med, Bristol, Avon, England
Moore, Simon C.
Hickman, Matthew
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Univ Bristol, Sch Social & Community Med, Bristol, Avon, EnglandUniv Bristol, Sch Social & Community Med, Bristol, Avon, England
Hickman, Matthew
Macleod, John
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Univ Bristol, Sch Social & Community Med, Bristol, Avon, EnglandUniv Bristol, Sch Social & Community Med, Bristol, Avon, England
Macleod, John
Heron, Jon
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Univ Bristol, Sch Social & Community Med, Bristol, Avon, EnglandUniv Bristol, Sch Social & Community Med, Bristol, Avon, England