Live cells infected with Enterovirus A71 are specifically extruded from human colonoids

被引：0
|
作者：
Moshiri, Jasmine [1 ]
Kirkegaar, Karla [1 ]
机构：
[1] Stanford Univ, Sch Med, Stanford, CA 94305 USA
来源：
NATURE MICROBIOLOGY | 2023年 / 8卷 / 04期
关键词：
D O I：
10.1038/s41564-023-01340-y
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Colonoids derived from adult human stem cells support growth of human enterovirus. Instead of spreading through the epithelium or lysing infected cells, virus is released within intact infected cells. Infected cells are detected by force-sensing ion channels, a mechanism akin to that used for normal turnover of uninfected epithelia.
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收藏
页码：565 / 566
页数：2
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