Say YES to single-gene lysis!

被引:0
|
作者
Nabhani, Ali [1 ]
Morehouse, Benjamin R. [1 ,2 ]
机构
[1] Univ Calif Irvine, Sch Biol Sci, Dept Mol Biol & Biochem, Irvine, CA 92697 USA
[2] Univ Calif Irvine, Sch Pharm & Pharmaceut Sci, Dept Pharmaceut Sci, Irvine, CA 92697 USA
关键词
PHI-X174; LYSIS; SLYD;
D O I
10.1016/j.chom.2023.08.011
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Viral strategies to lyse host microbes can sometimes involve just a single gene, although the mechanism of action can be hard to discern. In Science, Orta et al. present structures of a protein complex in which protein E of bacteriophage phi X174 functions to inhibit host peptidoglycan synthesis, thereby inducing lysis.
引用
收藏
页码:1420 / 1422
页数:3
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