Efficacy and safety of perampanel in a randomized, placebo-controlled trial with an open-label extension in patients with seizures associated with Lennox-Gastaut syndrome (LGS)

被引：0
|
作者：
Porter, Brenda [1 ]
Kira, Ryutaro [2 ]
Lee, Jeehun [3 ]
Aeby, Alec [4 ]
Patten, Anna [5 ]
Ngo, Leock [6 ]
机构：
[1] Stanford Univ, Dept Neurol & Neurol Sci, Palo Alto, CA USA
[2] Childrens Hosp, Dept Pediat Neurol, Fukuoka, Fukuoka, Japan
[3] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, Seoul, South Korea
[4] Univ Libre Bruxelles, Hop Univ Enfants Reine Fabiola, Pediat Neurol, Brussels, Belgium
[5] Eisai Europe Ltd, Biostat, Emea, Hatfield, Herts, England
[6] Eisai Inc, Clin Res, Nutley, NJ USA
来源：
JOURNAL OF THE NEUROLOGICAL SCIENCES | 2023年 / 455卷
关键词：
D O I：
10.1016/j.jns.2023.121563
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
121563
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Topiramate in Lennox-Gastaut syndrome: Open-label treatment of patients completing a randomized controlled trial
    Glauser, TA
    Levisohn, PM
    Ritter, F
    Sachdeo, RC
    [J]. EPILEPSIA, 2000, 41 : S86 - S90
  • [2] Open-label extension study of the efficacy and safety of rufinamide adjunctive therapy in patients with Lennox-Gastaut syndrome
    Glauser, T
    Kluger, G
    Sachdeo, R
    Krauss, G
    Perdomo, C
    Arroyo, S
    [J]. EPILEPSIA, 2005, 46 : 408 - 408
  • [3] Long-term Safety and Efficacy of Cannabidiol (CBD) in Patients with Lennox-Gastaut Syndrome (LGS): Results from Open-label Extension Trial (GWPCARE5)
    Halford, Jonathan
    Marsh, Eric
    Mazurkiewicz-Beldzinska, Maria
    Gunning, Boudewjin
    Checketts, Daniel
    Roberts, Claire
    Thiele, Elizabeth
    [J]. NEUROLOGY, 2018, 90
  • [4] Long-term Safety and Efficacy of Cannabidiol (CBD) in Patients with Lennox-Gastaut Syndrome (LGS): Results of the Open-label Extension (OLE) Trial (GWPCARE5)
    Thiele, E.
    Marsh, E.
    Halford, J.
    Mazurkiewicz-Beldzinska, M.
    Gunning, B.
    Checketts, D.
    Roberts, C.
    [J]. ANNALS OF NEUROLOGY, 2018, 84 : S336 - S336
  • [5] Efficacy and Safety of Fenfluramine for the Treatment of Seizures Associated With Lennox-Gastaut Syndrome A Randomized Clinical Trial
    Knupp, Kelly G.
    Scheffer, Ingrid E.
    Ceulemans, Berten
    Sullivan, Joseph E.
    Nickels, Katherine C.
    Lagae, Lieven
    Guerrini, Renzo
    Zuberi, Sameer M.
    Nabbout, Rima
    Riney, Kate
    Shore, Svetlana
    Agarwal, Anupam
    Lock, Michael
    Farfel, Gail M.
    Galer, Bradley S.
    Gammaitoni, Arnold R.
    Davis, Ronald
    Gil-Nagel, Antonio
    [J]. JAMA NEUROLOGY, 2022, 79 (06) : 554 - 564
  • [6] Open-label, uncontrolled retrospective study of perampanel in adults with Lennox-Gastaut syndrome
    Crespel, Arielle
    Ngoc Phuong Loc Tang
    Macorig, Greta
    Gelisse, Philippe
    Genton, Pierre
    [J]. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2020, 75 : 66 - 69
  • [7] Efficacy and safety of Clobazam for seizures associated with Lennox-Gastaut Syndrome (LGS): results of a Phase III study
    Conry, J. A.
    Ng, Y. T.
    Drummond, R.
    Stolle, J.
    Owen, J. R.
    Weinberg, M. A.
    [J]. ANNALS OF NEUROLOGY, 2011, 70 : S113 - S113
  • [8] Cannabidiol in patients with Lennox-Gastaut syndrome: Interim analysis of an open-label extension study
    Thiele, Elizabeth
    Marsh, Eric
    Mazurkiewicz-Beldzinska, Maria
    Halford, Jonathan J.
    Gunning, Boudewijn
    Devinsky, Orrin
    Checketts, Daniel
    Roberts, Claire
    [J]. EPILEPSIA, 2019, 60 (03) : 419 - 428
  • [9] Long-term Safety and Efficacy of Add-on Cannabidiol (CBD) Treatment in Patients with Lennox-Gastaut Syndrome (LGS) in an Open-Label Extension (OLE) Trial (GWPCARE5)
    Perry, M.
    Patel, A.
    Gil-Nagel, A.
    Chin, R.
    Mitchell, W.
    Weinstock, A.
    VanLandingham, K.
    [J]. ANNALS OF NEUROLOGY, 2019, 86 : S76 - S77
  • [10] Efficacy and safety of rufinamide adjunctive therapy in patients with Lennox-Gastaut syndrome (LGS): A multicenter, randomized, double-blind, placebo-controlled, parallel trial: LBS. 001
    Glauser, T
    Ohio, C
    Kluger, G
    Sachedo, R
    Krauss, G
    Perdomo, C
    Arroyo, S
    [J]. NEUROLOGY, 2005, 64 (10) : 1826 - 1826
12345