Chemo-selective Stille-type coupling of acyl-chlorides upon phosphine-borane Au(<sc>i</sc>) catalysis

被引：1

作者：

Hidalgo, Nereida ^{[1
,2
]}

Le Gac, Arnaud ^{[1
]}

Mallet-Ladeira, Sonia ^{[3
]}

Bouhadir, Ghenwa ^{[1
]}

Bourissou, Didier ^{[1
]}

机构：

[1] Univ Paul Sabatier, CNRS, Lab Heterochim Fondamentale & Appl LHFA UMR 5069, 118 Route Narbonne, F-31062 Toulouse 09, France

[2] Univ Seville, Dept Quim Inorgan, Seville 41071, Spain

[3] Inst Chim Toulouse FR 2599, 118 Route Narbonne, F-31062 Toulouse 09, France

来源：

CHEMICAL SCIENCE | 2024年 / 15卷 / 14期

关键词：

GOLD CATALYSIS; LIGANDS; REACTIVITY; DERIVATIVES; COMPLEXES; CHEMISTRY; EFFICIENT; SILVER;

D O I：

10.1039/d3sc06193k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Phosphine-boranes do not promote oxidative addition of acyl chlorides to gold, but the phosphine-borane gold triflimide complex [(Pr2P)-Pr-i(o-C6H4)BCy2]AuNTf2 was found to catalyze the coupling of acyl chlorides and aryl stannanes. The reaction involves aryl/chloride-bridged dinuclear gold(i) complexes as key intermediates, as substantiated by spectroscopic and crystallographic analyses. Similar to Pd(0)/Pd(ii)-catalyzed Stille coupling with phosphine-borane ligands, the gold-catalyzed variant shows complete chemoselectivity for acyl chlorides over aryl iodides and bromides, enabling straightforward access to halogenated aryl ketones.

引用

页码：5187 / 5191

页数：5