The Landscape of Circular RNAs in Cardiovascular Diseases

被引：16

作者：

Long, Qi ^{[1
,2
,3
]}

Lv, Bingjie ^{[1
,2
,3
]}

Jiang, Shijiu ^{[1
,2
,3
]}

Lin, Jibin ^{[1
,2
,3
]}

机构：

[1] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Cardiol, Wuhan 430022, Peoples R China

[2] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Hubei Key Lab Biol Targeted Therapy, Wuhan 430022, Peoples R China

[3] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Hubei Prov Engn Res Ctr Immunol Diag & Therapy Car, Wuhan 430022, Peoples R China

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2023年 / 24卷 / 05期

基金：

中国国家自然科学基金;

关键词：

circRNA; cardiovascular disease; biomarker; ISCHEMIA-REPERFUSION INJURY; VASCULAR ENDOTHELIAL-CELLS; HEART-FAILURE; MYOCARDIAL-INFARCTION; MESSENGER-RNA; STEM-CELLS; EXPRESSION; SENESCENCE; APOPTOSIS; HYPOXIA;

D O I：

10.3390/ijms24054571

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cardiovascular disease (CVD) remains the leading cause of mortality globally. Circular RNAs (circRNAs) have attracted extensive attention for their roles in the physiological and pathological processes of various cardiovascular diseases (CVDs). In this review, we briefly describe the current understanding of circRNA biogenesis and functions and summarize recent significant findings regarding the roles of circRNAs in CVDs. These results provide a new theoretical basis for diagnosing and treating CVDs.

引用

页数：20